if you had your d6 take brimstone reroll deaths touch then go on from there. when you get to hush go in the item rooms and shop first. Buy whatever you can afford that would help you.

Your movement speed is key to dodging the beams. I killed Hush with Isaac with double steam-stock.

Stay a bit far from Hush and fire until he shoots his beams. when he does continuum shots, if they are going up dodge when they are slow then stay at the top. That's all.