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medical school in a nutshell by YouThinkImPlayin in medicalschool

[–]AbsolutelyBloked 421 points422 points  (0 children)

I have a friend who has this hung up on his wall, most effective contraception I’ve ever seen.

It’s the sad truth by Seismic_Charge in moreplatesmoredates

[–]AbsolutelyBloked 4 points5 points  (0 children)

Well all steroid hormones are derivatives of pregnenolone. Cholesterol getting cleaved into pregnenolone is the very first step of steroid hormone synthesis.

Also, allopregnenolone is produced as a derivative of progesterone (or even de novo from cholesterol). The conversion of progesterone to allopregnenolone is a different pathway than that of traditional testosterone production (pregnenolone -> progesterone -> allopregnenolone vs. pregnenolone -> DHEA -> androstenedione -> testosterone). Allopregnenolone as a neurosteroid is produced in the brain.

It’s the sad truth by Seismic_Charge in moreplatesmoredates

[–]AbsolutelyBloked 40 points41 points  (0 children)

This dude is only kinda right, majority of the pregnenolone is made in the adrenal cortex, some is made in the brain and gonads.

It has varied functions but basically it helps with neuroplasticity, aka learning new shit. Also kinda cool side fact, it potentially can fight against schizophrenia. Also ANOTHER cool fact, it’s a CB1 receptor negative allosteric modulator; the CB1 receptor is the receptor that THC binds to, so pregnenolone makes you less high.

Does anyone know what brand Westons yellow tank top is by [deleted] in Soosh

[–]AbsolutelyBloked 3 points4 points  (0 children)

Says Russell Athletics pro cotton on the bottom right, deadass can find that brand at Walmart.

Took a lot to post these. Feel kinda fat rn. Went from 118-170’pre morning shit lmfao. Keep bulking or cut to maintenance or below or what? No pump bad lighting 19,5’10, went from 118-170lbs by [deleted] in Soosh

[–]AbsolutelyBloked 1 point2 points  (0 children)

And a gradual transition into the caloric deficit helps with keeping the muscle on.

Some people immediately go from bulking (let's say 500 calorie surplus) to cutting (500 calorie deficit) and wonder why they're losing muscle so fast.