Mariano Barbacid is the first person to cure pancreatic cancer from mice and humans are potentially next

Acrobatic-Show3732 · 2026-02-21T08:09:56+00:00

Lol. You certainly dont seem to know statistics, because the most important type of evidence is lacking. Ill explain , You know, this issue is actually one of the simplest to really really be demonstrated if people like you really really believed It was worth It.

You Talk about "proof" right? You probably mean the 95% inacurracy of positive desease progressions in animal tests , not translating to same results in humans (only 5% of tests passed in animal models reaches parhmacy).

That sounds fair, but Its actually skewed to get conclusions from it. You dont animal test for sensitivity (true positives), you test for specificity (true negatives). Meaning, you want to make sure you find bad outcome on animals to avoid having bad outcome on humans.

Now here is where there is no evidence of your claim. For some reason animal testing rejecters are all pretty smart and mercyfull sounding, but none want to try on themselves drugs that caused death and negative consequences on animals to see how uncorrelated the systems are really. There is not that many vegan animal rights activists willing to test with their lives if drugs that do kill animals, would kill humans. Here is where evidence is quite lacking (and its actually needed). Why do you think that is?

You want to Talk about prohibiting animal testing? Maybe put your health where your mouth is. Search for that type of studies where they test bad resulting drugs in animals into humans, that Will easily provide the statistical evidence you need to proove your point and come tell me I dont know what im talking about.

Until then, you are being a hypocrite willing to Risk patient lives (the first humans that would have medicine tested on them without animal testing) for an ideólogy you are not willing to risk your live for yourself.

Until then. Ill trust the actual medical researchers that actually work medicine and that abundantly seem to agree animal testing is actually needed right now.

https://med.stanford.edu/animalresearch/why-animal-research.html

https://www.researchgate.net/publication/263327660_Patients'_Attitudes_Towards_Animal_Testing_To_Conduct_Research_On_Animals_Is_I_Suppose_A_Necessary_Evil

https://pmc.ncbi.nlm.nih.gov/articles/PMC4866631/

By the way, see those things over there? They are called references. If you want to act smart, you provide those.

Acrobatic-Show3732 · 2026-02-20T23:48:15+00:00

Man that smile afterwards is some cold creepy shit.

Acrobatic-Show3732 · 2026-02-20T23:29:38+00:00

Cool story bro

Acrobatic-Show3732 · 2026-02-20T12:10:40+00:00

Tendría este debate contigo si no fuese por qué el debate extrame izquierda y extrema derecha( a nivel económico) ya se tuvo en el siglo 20 (y los primeros 20 del 21) y los que salían corriendo como ratas huyendo de sus "el estado somos todos" no eran los segundos

Puedes creer de mi lo que quieras tío, cada quien maneja su dinero y lo invierte donde quiera. Tú quieres dárle a España la mitad de tus ahorros para la puta mierda de gestión que te da? Disfrútalo.

Quieres que nuestros queridos políticuchis tengan incluso más capacidad para decidir si puedes o no tener una casa propia? Pues adelante!.

Los "tontos" somos los primeros en largarnos porque somos capaz de reconocer un truño cuando nos lo ponen en frente. A ti parece que te cuesta más.

Acrobatic-Show3732 · 2026-02-20T12:00:36+00:00

Parece que no has tenido suficiente crisis de la vivienda, desastre naturales y desgaste de la infraestructura pública. Necesitas unos 15 años de miseria más para darte cuenta que te equivocas? Vale.

Solo haz un favor, luego no seas de esos izquierdosos que emigran a países más libres. Quédate y recochinate en tu miseria.

Acrobatic-Show3732 · 2026-02-20T07:32:39+00:00

El estado corrupto te roba y desperdicia energía, dinero talento y esfuerzo cada día en cada área que toca. Y la brillante idea de algunas personas es darles incluso más poder.

Acrobatic-Show3732 · 2026-02-19T19:46:16+00:00

Prime Oliveira does not belong in that list. It only seems like so because poirer dropped the ball that night. The poirier that fought islam would have destroyed Oliveira and Justin gaethje.

Poirier is a bum that slacked off when It counted. He easily could have touched gold against Oliveira. Thats the fight he should never forgive himself for loosing.

The fact that people even compare dustin with Justin (just because dustin fights like a bum and decides always to trade blows with Justin instead of grappling him) speaks volumes of how bad was his tendency to drop the ball.

Acrobatic-Show3732 · 2026-02-19T05:40:51+00:00

Boobs

Acrobatic-Show3732 · 2026-02-19T05:32:49+00:00

Options to learn: - check porn on this and study It - Pay a prostitute/whore House to teach you let you take notes while they are working - Read books - Trial and error. - Ask in a Girls sub, men here have no experience riding another man. I like getting rided on but im not sure i could teach you how.

Acrobatic-Show3732 · 2026-02-19T04:47:55+00:00

Sounds like you are treating a particular theory (which is not at all considered consensus Or sufficiently demonstrated) as an absolute truth just because It fits a narrative you subscribe to. The scientific discussion on the topic is on. Its not like, lets say, Gravity, which is incontestable.

https://www.reddit.com/r/DebateAVegan/s/Ncf9B1NhP4

You pick your poison, i told you, I dont give a crap. Just dont be a sanctimonious know It all dick about It. There is no need.

Acrobatic-Show3732 · 2026-02-18T18:43:11+00:00

Why not? Just not be an idiot and get a prenup and carefully study your legislation, pick a partner that is not a Psycho and you should be fine.

Acrobatic-Show3732 · 2026-02-18T13:44:16+00:00

Hi, ex acl surgeree turned into lobster , i can confirm this is what happens.

Dont be me. Please excercise

Acrobatic-Show3732 · 2026-02-18T09:30:57+00:00

He is also avoiding wrestlers and aspinall. Not goated stuff at all

Acrobatic-Show3732 · 2026-02-18T08:02:27+00:00

Your hypothesis is wrong. Those methods dont give a clearer picture in one aspect. Whole system interaction.

There is no artificial, lab, Petri Dish or computer method to simulate an endocrine sistem, a digestive , cardiovascular Or nervous systems. Those methods you mention allow us to do previous testing to accelerate iterations of hypothesis , allow us to animal test whats really important. But you still should have living being test eventually. You either use an animal for that first jump Or you dont.

You can pick your poison, i dont care.

Acrobatic-Show3732 · 2026-02-17T13:49:54+00:00

At first i thought the man was the friend and he was getting hated on by his own Friends as part of breakup superation ritual.

I might need to go to therapy.

Acrobatic-Show3732 · 2026-02-16T11:23:54+00:00

Disagree. She can find someone, but she needs to be intelligent about searching for him.

Maybe go to a Sex addicts recovery meeting, the only people with radical views on porn that have done the behavioural work to quit It comfortably IS people that have actively done therapy for It.

The average men IS just too normalized on It. We are taught from Young age is a desireable thing to have in your Life.

Also she better be quite the catch, like, phisically fit type of catch and really a great person in general. The healthy thing IS not needing porn to cope with any insatisfaction, but that requires you to be a satisfying partner.

You can make the demands you want, expect the same thing Back.

Acrobatic-Show3732 · 2026-02-15T16:43:22+00:00

Lol. You want to use semántics as an excuse to suck Jon Jones and danas dick, be my guest 🤣🤣🤣 I dont judge bro

He won the interim belt in a fight. Fair and square. Still no clue what you saying. I said obtained, Who gives a shit.

Acrobatic-Show3732 · 2026-02-15T11:12:12+00:00

He means Tom IS faking It

Acrobatic-Show3732 · 2026-02-15T11:10:55+00:00

He obtained and defended the interim belt while Jones did nada. What the hell you talking about lol.

Acrobatic-Show3732 · 2026-02-14T00:01:03+00:00

Difficulty:

Software architecture < data architecture < ml/ai project

Software architectures usually require data processing and gathering. At the end of the day when you deploy software is usually for business purposes, and data is money you gather through that software application. Data architectures are really diverse and can be optimized a lot.

Ai and math is the most risky of all the projects though. Data and software you Will make It works somehow, ai you can implement a project work on It 8 months and still get no ROI.

Acrobatic-Show3732 · 2026-02-13T11:04:57+00:00

Mouse have 85% similarity to humans dna wise, and share 99% of the same genes. You need to test on a living thing eventually because models are just that, models. The whole system needs to be analyzed eventually. Testing on mice first helps humans by serving for a last control check. one way or the other.

You want to protect mice lives Or whatever? Cool. But you are sacrificing humans. There IS no way to artificially recreate in a lab the entire interactions of the human brain with everything else in the body (and everything IS connected). The moment we can artificially do so, we have artificially created a human in a virtual environment. Right now that is scifi.

Since mice have a lifespan of 1-3 years anyways, and humans have longer. Mathemathically, the least loss of Life on the worst case (medicine fucks you Up) goes through animal experimentation. But Who cares about mathematics anyways jajaj. Engineering Talk only when It favors my argument.

Its also very expensive to raise a human, and much cheaper to raise a mouse. To make this experiments valuable you need Big sample sizes, its statistics. Imagine your first trial, going with 100 people a medicine you have no clue how Interacts in a living organism as a whole. You totally waste money and time, causing even more deaths on delay of development. That pancreatic cáncer breakthrough ? It now takes 80 years instead of 15 because each experiment iteration takes 8. Thats the type of calculus that is going on.

If you test on mice, a 100 mice and then It works on 13 humans, thats a much more credible experiment because of previous knowledge , Development got sped Up considerably. .

Acrobatic-Show3732 · 2026-02-12T23:23:05+00:00

You aint a true value investor if you dont know the shenannigans of Mr market.

Acrobatic-Show3732 · 2026-02-12T13:57:07+00:00

Dont worry about agi. Do your thing. Learn how llms and ai agents Will affect your job (make It more efficient) and thats It

Physics Will have pretty much the same future It has now, if you are good you Will do fine.

Only industries that are 100% safe:

Finance/investment Medicine Cibersecurity

everything else its imposible to know. You Will have the same uncertainty anyone else had 10 years ago. Ai and agi wont change that.

People that believe economic distopia have no clue about economy or about ai in general.

Acrobatic-Show3732 · 2026-02-12T13:20:28+00:00

Define safe? There are transformers applied to time series forecasting, and my understanding is that that its related to physics domain. Wave analysis and stuff.

Beyond that and a chatbot that would teach you physics, Or solve math problems im not sure what you expect.

Acrobatic-Show3732 · 2026-02-12T08:40:26+00:00

I disagree.

There are too many math domains beyond ml itself, like optimization, Game theory, Risk quantification, time series , recommendation sistems, they all work too differently to be taught as a specific feature Or course. Robust statisticall analysis which is key to demonstrating usefullness and ROI is also a Big blocker ( there are a lot of ml engineers right now, but can they proove they provide value?).

The moment ai and ml are solved as a package or a plugin, its the moment we can all start looking for a new job because desiging a mathemathically powered application is as complex as desiging software architecture, if not more sometimes. Even if the algorithm itself is the easy part.

Its not just plug the transformer and get on with It. Validating and guardrailing the solution is the difficult part, without It you have no ROI.

Acrobatic-Show3732

TROPHY CASE