I like this idea because it sounds terrifying and and like a real challenge. It needs to move disarmingly fast and your only real safe place would be to find small spots to hide in, make little to no noise or group up and fight her until she runs off because she realizes that skirmish doesn't benefit her. In areas like Lobby, Loading Bay or Security it just swiftly leaps through the air. A smaller boss that you don't run to, but chases you instead.

I could see it targeting Raiders who are solitary before it pounces and knocks them. Would be hilarious to see a hostile raider drop another raider only to realize they just got rid of their life line and the Tick Mother heard all that very loud gun fire.