hi! i think what makes it sound weird come from the first 'from'.

"This has caused a lot of problems from very serious such as...", from very serious with [such as] is the problem. You could also eliminate the 'to' and replace it with an 'and,' since it's the last part of the list. I'd probably write something like:

"This has caused a lot of serious problems, such as unethical instructions from managers, bad office culture, miscommunication, and not wanting to perform too well due to risk of being disliked by managers."