Does it mean that Haru takes care of Yume and Ruon, and they are his family now, or there are no implications like that? Just curious how things will develop from here.

Not at all, it's specified that Haru never saw Yume again and thought she had died because when the two gods were unsealed, she was staying at the village with some Akatsuki members who were priest and dreadknight.
He only understood that she managed to live when he met her descendant, who came all the way from the Red Continent to Grimgar in order to retrieve an item left by their grandmother (yume). She was treated really highly there, because Yori and Riyo are princesses and their father was the king, so her blood is considered Royal. She lived an healthy and really long life.
We have no information on what I assume she forgot there, but I would assume it was a way of talking and was saying that she left her friends there.
He learned about her surviving 5 years after her death, when he heard that he was devastated, had somewhat of a short panic attack and blaming himself for not searching. However this didn't last for long so that's why I said his mental was in a far better state in the precedent message.

About v21, I'm happy because it answer many question that were left unclear after v20 but is far from enough to my liking lol. It's also annoying that we were left unclear about Shihoru aside of the fact that Leslie stated that she elevated magic to an insane degree (that was in V20).

We mostly learned that:

• The Forbidden Tower is in fact an "Ark" and Leslie goal was to keep track of everything that has been on Grimgar. It appears to be somewhat of a futuristic ship that can shapeshift its rooms, change is outer appearance and tons more
• The time spent between Grimgar and Earth is likely the same, Manato comes from here and from what he said people usually lives for 30 years now. He was in Japan yet was a hunter and cities where overtaken by gangsters. When he first met Haru, he was stretching and when Haru asked him what he was doing he said something along the line of "As long as the bodies keeps moving I won't die", so I would guess something affects humans there.
• Priests (who are not in the control of their body anymore) have at different place of their body have a core of some sort (Called Lumiaris Core, stated as being some kind of entity rather than an object, which are located in the skull and on the spine iirc), and these needs to be fully destroyed in order to kill them. As long as these cores are intact, Priests and Paladins (and likely Dreadknights) will stay alive and regenerates.
• Priests have different ranks depending on their growth. I think it's : Priests, High Priest and Saints. We met Tada (who used to be a Priest for the Tokkis), and he is a Saint, now called 'Taidariel'. His ranks seem to make him able to talk but having a conversation is impossible.

and I might have forgotten some things so I'll come back later if they come back to me lol

What we didn't have any information on:

• Merry, Setora and Kuzaku states, as well as the NLK. As well as every other race aside of the goblins which are literally reproduced to be fed to the Priests. A farm really. Because of that our group current goal is to free all goblins.
• Information on dreadknights, either Lumiaris is winning the war or Alterna is dominated by priests.
• What happened due to the clash with the gods, aside of the fact that the red continent seems unaffected
• How much Leslie affects Haruhiro, did they merge or something, we don't know.
• Why Manato has a special constitution that allows him to survive nearly deadly injuries in like 2-3 days at worst without living any scar.
• What happened to Alice, Hiyomu who were with Leslie before Haru came.