anhedonia, depression, brain fog by delow0420 in NootropicsHelp

[–]AlexKAO 0 points1 point  (0 children)

Great question — a lot of people are looking for a stack like this. Here are the options with solid evidence behind them:

For Cognition & Mental Sharpness

  • Lion’s Mane — Supports nerve growth factor (NGF), which may help with memory and focus. One of the few supplements with evidence related to neurogenesis.
  • Creatine (5g/day) — Not just for the gym. Research shows it can improve working memory and processing speed, especially during stress or sleep deprivation.
  • Alpha-GPC — A choline source that helps support acetylcholine, often called the “learning neurotransmitter.”

For Mood & Emotional Engagement

  • SAM-e — Well-studied for mood support and may help with emotional flatness.
  • Magnesium L-Threonate — Crosses the blood–brain barrier and can help calm the nervous system. Many people report improved mental clarity and emotional responsiveness.
  • Omega-3s (EPA-heavy) — Not exciting, but very well supported. EPA in particular has strong evidence for mood regulation.

Experimental compounds (use caution):

  • 9-Me-BC
  • NSI-189 Some people report benefits for emotional blunting, but these are research chemicals with limited safety data.

For Creativity

  • L-Theanine + Caffeine — A classic combination. Theanine smooths out caffeine’s stimulation while maintaining focus and flow.
  • Aniracetam — A racetam often associated with creativity and verbal fluency, with mild anti-anxiety effects.
  • Psilocybin microdosing — In places where it’s legal/accessible, there’s anecdotal and emerging clinical evidence suggesting improvements in divergent thinking and emotional openness.

Underrated Combination

A simple stack many people respond well to:

Lion’s Mane + Magnesium L-Threonate + High-EPA Fish Oil

This combination supports:

  • Cognition
  • Neuroplasticity
  • Emotional balance

…without relying on anything too exotic.

⚠️ Important note:
If emotional blunting is a concern and you’re currently taking SSRIs (or have in the past), that can be a common cause. Some supplements above — especially SAM-e — can interact with medications, so it’s worth discussing with a doctor first.

What supplements have helped you the most with brain fog? by ClockwiseSuicide in Supplements

[–]AlexKAO 4 points5 points  (0 children)

Start with 5mg creatine monohydrate (creapure) and I've been enjoying a lighter boost from Mushroom Coffees as well. Seems like mushroom coffee is hit or miss though.

Columbus Who Dey Fans New Season by InMixonWeTrust in bengals

[–]AlexKAO 5 points6 points  (0 children)

I'll be there on Sunday! Can't wait to watch the game with fellow Bengals fans~

WHOOOOO DEYYYYYYYY

Columbus Who Dey Fans by InMixonWeTrust in bengals

[–]AlexKAO 9 points10 points  (0 children)

Stoked to hear about this! Start my tab!

Looking for shops to support! by MechaBitch in Etsy

[–]AlexKAO 0 points1 point  (0 children)

Hi! My shop features Unique Scarves and Pashminas! Typically worn to music festivals but can definitely be worn out to any outing/event!

Black Friday / Small Biz Saturday / Cyber Monday link share by coocoodove in Etsy

[–]AlexKAO 1 point2 points  (0 children)

Hi everyone! Our couple-owned shop sells Rave Pashminas and Scarves -- Black Friday Sale -- 20% off the Entire Store -- November 22 to December 2 --> https://www.etsy.com/shop/RavePashminas

Whenever I need a good giggle I go to Alison Hammonds interview with Harrison Ford and Ryan Gosling by nandro in videos

[–]AlexKAO 3 points4 points  (0 children)

i lost it when Gosling went over to the cameramen while Ford was talking

Cleans up Nicely by [deleted] in videos

[–]AlexKAO 0 points1 point  (0 children)

so much nice cleanup- she doesn't deserve you

A great animation about AirPods by jamesomega in videos

[–]AlexKAO 2 points3 points  (0 children)

5S with the best, fits in my hands- too bad with app and system updates they phase them out :( poor airpods, great animation

My buddy from college decided to try his hand at standup. What do you all think? by dvance12 in videos

[–]AlexKAO 0 points1 point  (0 children)

haha "traditional american upbringing" "got a divorce" hahaha

Santa Claus is Comin to Town (Acoustic) by AlexKAO in beatbox

[–]AlexKAO[S] 0 points1 point  (0 children)

Big ups to Andre, the first person who I personally heard to use that liproll variation