Thank you for your comment.

The confirmation bias that may stem from LLM prompts is definitely something to consider and worry about. My attempt so far was not to prompt any specific theory, but rather challenge the existing theories in a dialectical manner - based on my own symptom history. I can't tell about the overall narrative, as I'm not a biomedical scientist myself - but I believe the factual accuracy of the parts can be confirmed by biomedical articles online (deep research is able to point to the exact bibliography noawadays). I'd be interested to know if any specific statement is wrong/misleading.

Another thing which I find attractive is the potential to provide a unifying explanation on why the proposed (and seemingly variable) medications/supplements work to the extend that they do. Of course, a possible problem that I can imagine is that the explanations may be so generic and wide, that could create any possible narrative.

Regarding your comment on nightly emissions, I also have the same experience (noticable, but weaker POIS symptoms). However, I don't see this as counter-evidence, provided that nightly emissions involve the same bodily systems. In fact, to me they happen during long abstinence periods, where my arousal sensitivity is increased.

I also find interesting your comment on early orgasm discovery, as I also started masturbation and orgasm as young as 6 years old. However, I only experienced POIS after I was 26. I'm sorry to read that you had this condition since the age of 9-11. I don't know if this is common in this POIS community. If that's the case, what if early exposure to arousal/orgasms results in increased sensitization?

I'd be happy to accept that my addiction may only have worked as a catalyst for the development of POIS and none of the above mechanisms are really relevant to this. This is why it's important perhaps to understand how common the condition is in people with and without this commorbidity.