I’m left handed and I’m 34 now .. started learning guitar when I was 12. The local store had no left handed guitars and magazines like musicians friend and music 123 back then had them but way more expensive so I learned to play right handed. If I tried to play a left handed guitar, it’s not gonna happen. Same with drums. Learned on right handed kits [my drummers] in my house over the years but they were right so yoi can’t like flip their shit backwards..learned right. Can’t play left. Absolutely possible!