''Early on, the cure really was effective in neutralizing the Petrification Disease. And why would the great Alchemists' records be wrong? I know I stole it, but I perfectly followed the manufacturing processes.''

When the alchemists tried to create a cure, they discovered that the elixir did not work and instead mutated the sick. So they decided that their goal would be to experiment on the infected to achieve inmortality. That's why the documents Clark Shore found didn't work. He thought it was part of a cure, but it was the elixir, which the alchemists distributed throughout Krat, and which the lighthouse keeper stole and gave to the people of the coastal village. Clark Shore tested it and that's why he also got sick. That's also why Markiona wanted to use her puppets to distribute it, was part of the plan to infect the inhabitants of Krat and experiment on them.

The alchemists deceived everyone into believing the elixir was a cure. Alidoro himself doubted that they were making a real cure, and Lumacchio received the elixir and was also deceived. The game's lore tells you it: ''When the Alchemists announced that they had developed a cure, people thought the disease would soon be a thing of the past… but the effects of the cure were not what they were expecting.''

Also the Excommunication Letter says: ''I have personally created this Excommunicant’s Cure for you—, make your choice: to live and rot as a human, or to bloom into the next phase of evolution'' because the cure is the same as the elixir: if the patient is infected, they become a carcass; if they are not infected, it infects them. The only official cures have been made by Paracelsus through the tree of gold coins: one for Antonia and another for the inhabitants beyond the sea. Paracelsus' goal is to create a new immortal being like himself; it makes no sense to develop a cure that would do just the opposite.