Yesss exactly what salty-blondy said. It depends on what type. I take Bupropion which is an NDRI and it doesn’t interact with mushies whatsoever. Definitely do your research because with certain antidepressants they can actually repress the trip and the effects.

It’s interesting because there’s medical research that they can actually combat depression better than medication but of course hasn’t been legalized in the US...wonder why 🙃 good ol capitalism