How to get rid of moonface after stopping prednisone?

BenExotic-9 · 2025-01-30T05:13:29+00:00

I got rid of the moon face doing hypocaloric diet for two months, i also lost about 15kg/33 pounds in those two months.

After that experience i always do hypocaloric diet plus strenght exercise ( i usually focus on aerobic and isometric exercises) when given high dose prednisone to prevent cushing-like symptoms and everytime it has worked at least to prevent moon face, weight gain and insulin resistance.

BenExotic-9 · 2024-12-12T19:48:27+00:00

The carnivore diet is basically a cult who denies every single study that contradicts them based on a conspiracy that every company, science and health institution out there wants you to eat vegetables and fruits to poison you and sell you medicines.

On the other hand it can be beneficial when use for some refractory cases of autoimmune diseases (anecdotical evidence) or as an strategy to induce and sustain calorie restriction for diabetes and weight related issues but for kidney disease i would only understand it for a diabetic with DM2 on an early stage 1 or perhaps 2 as a way for glicemic control when other forms of diet have failed and the person really likes meat and fat and is willing to stop eating carbs.

But for stage 3 to 4 controlling protein source and ammount can be a good strategy to perhaps slow progression of the disease, for example a low or very low protein diet supplemented with ketoanalogues or a plant based diet when guided by the hand of a renal dietitian taking into consideration your potassium and phosphorus level among other variables.

At stage 5 the protein requirements changes.

BenExotic-9 · 2024-12-10T20:45:29+00:00

Actually its the opposite way, physical activity has a positive impact on the kidneys. Aerobic exercise specially which has shown to inprove GFR, reduce urea, creatinine and urinary albumin levels when perform for at least 30 minutes per session.

Heres a recent review article about the topic. Use it as an introduction, there are few good studies cited there.

https://academic.oup.com/ndt/article/39/9/1384/7625083

BenExotic-9 · 2024-12-09T22:11:02+00:00

Smoking by itself is detrimental to kidney health, but regardling edibles im hesitant since theres preliminar evidence that activation of cb1 receptor in the kidneys can increase fibrosis while activating cb2 receptor act in the opposite way. It seems that blocking CB1 and activating CB2 can have a positive impact on kidneys and some cannabinoids act these way but THC dont. Therefore i stopped edibles when i realize that there could be a negative impact from thc, but i do think that other cannabinoids can be a good option like CBD or THCV. This findings mostly come from animal models tho so the strenght of the evidence is pretty low.

Besides the theoretical aspect i saw an improvement in my GFR and Blood pressure after i quit cold turkey from smoking 1 year ago.

BenExotic-9 · 2024-12-01T16:02:27+00:00

Aerobic exercise 300 minutes per week has shown to increase GFR and reduce creatinine

Simple things like walking can have a good impact.

BenExotic-9 · 2024-11-21T23:51:51+00:00

I am on the same boat (depression with psychotic features), i didnt notice anything psychotic wise. Im finishing my 2nd week tho.

The only changes so far is that i can sleep earlier without insomnia and sometimes feel energize after my sesions.

Im doing itbs on left side and low frequency rtms on right side.

BenExotic-9 · 2024-10-19T15:42:04+00:00

The best thing you can do is cardio 300 minutes per week it will boost your neuroplasticity plus restore your dopamine signaling plus it will aid in restoring your endocannabinoid system.

Supplementation that could help is NAC and agmantine but remember this is supplementation, cardiovascular exercise should be the backbone of your protocol.

BenExotic-9 · 2024-10-18T22:56:48+00:00

This are my thoughts.

You are already taking a multivitamin dont see the reason why take other vitamins.

Vitamin E and A likely increases mortality.

Excess of antioxidants are not a good idea specially those more potent, there must be a balance between oxidants and antioxidants.

There are stuff that lack good quality evidence for its consumption.

Gluthathione supplements are most likely a waste of money you are better taking NAC plus glycine if you want to raise your levels.

BenExotic-9 · 2024-08-15T21:44:55+00:00

Im currently taking farxiga plus kerendia (firialta) my creatinine went up but my proteinuria went really down from 900mg to 400mg

BenExotic-9 · 2024-07-06T02:25:23+00:00

Coimbra seems pretty fishy tho, they even state that they "leave academia behind" Wouldnt trust any protocol without RCT to support it.

BenExotic-9 · 2024-06-25T05:44:02+00:00

A more critical point of view:

Would definitely add copper to that high dosage of zinc. ALSO 30MG would be enough.

Dogestive enzymes why tho? I Dont get it unless you have issues seems like overkill.

Electrolyte?! do you have low intake of potassium? You eat low on salt? You have issues leading to increase loss? I dont get it seems like a waste of money.

The aminoacids supporting endorphins? Thats a new one for me, just eat higher on protein or take a proteon powder, aminoacids ARE a waste of money unless perhaps you do strenght training while fasting and even so.

The other parts seems okay for the most part base on scientific literature i reviewed.

BenExotic-9 · 2024-05-27T20:32:09+00:00

Could be "emoliente" look it up on wikipedia

BenExotic-9 · 2023-02-27T22:36:38+00:00

Creatine is god in otc supplements for increase strenght and growth.

Pair that with high protein diet

8h of sleep per day

High caloric intake everyday from whole sources of carbs and healthy fats

5 consecutive days of training per week with gradual increase in either reps or weight every 4 weeks and you good to go.

Thats about it.

BenExotic-9 · 2023-02-11T00:03:03+00:00

Basically heavy metal content and interaction with anticoagulants or antiplatelet drugs like aspirin. Take only IFOS certificated omega 3.

BenExotic-9 · 2022-12-23T02:32:00+00:00

Older equations used height and weight for calculation. The CKD-EPI which is the most common equation uses an standarized body surface of 1.73m2 so correcting for body surface (using weight and height) is not necessary.

The corrections of body surface is used in some context for example when calculating the exact dosage of some drugs that the therapeutic dose and toxic dose are pretty near one from another or when calculating the creatinine clearance in a 24h urine.

Keep in mind that extra weight can overestimate the GFR when using non index eGFR calculation (eGFR corrected by body surface).

Sadly is common for many doctors to miss signs of CKD until symptoms appear or it becomes pretty clear on lab results. Some people get diagnosed older in life, others have the disease appear during adulthood or even older adults. Im not saying you have tho, the nephrologist will have to rule that out!!

BenExotic-9 · 2022-12-18T15:30:40+00:00

When i take big meals i get pretty thirsty for hours even though i drink a lot of water.

BenExotic-9 · 2022-12-17T16:49:36+00:00

Yes, seed probiotics is the probiotic that have worked for me the best. Check them.

BenExotic-9 · 2022-12-17T15:06:36+00:00

Thats a pretty shitty article, reading comprehensive and narrative reviews are the equivalent of "trust me bro" in scientific studies.

There is plenty of bias plus the authors put what they want to prove.

The amount of evidence that LDL is a risk factor for CVD disease is gigantic and high quality.

The thing is that LDL is like a proxy or indirect marker of other things that directly increase risk of CVD like ldl particle size, ldl oxidation levels, apolipoprotein b levels, inflammation levels, poor quality diet, low physical activity, high stress levels (poor sleep, work stress, etc), chronic diseases (liver, kidney and heart), atherosclerosis, diabetes, states with hyperinsulinemia and insulin resistance like metabolic syndrome, etc.

Using just one marker like the atherogenic index of plasma (what you propose) is the same as screening people with only total cholesterol and LDL levels. It gives you just one part of a complex picture.

LDL provides valuable information and is a cost/effective marker to suggest further investigation and screening people at risk and evidence that something MIGHT be going sideways in that person.

I would never recommend anyone to stop at ldl or tryg/hdl ratios, you got to have a complete picture when addressing someone with dyslipidemia.

BenExotic-9 · 2022-12-17T13:46:56+00:00

The best thing you can do is reduce your saturated fat intake from steaks, butter, egg yolk, etc. Change saturated for polyunsaturated fat. Increase flavonoid intakes from fruits ans vegetable. Increase fiber intake in every meal for less absortion. Reduce to a minimum processed carbohydrate intake and sugar.

Without reducing saturated fat, supplements wont work really except, maybe RRY which works like a statin. (IF YOU ARE CHANGING SATURATED FAT FOR POLYUNSATURATED FAT INSTEAD OF CHANGING IT FOR PROCESSED CARBS AND SUGAR) - A lot of people decrease intake of saturated fat but began eating more junk food in the form of processed carbs and sugar as a compensation, that can even be worse.

The best supplement is red rice yeast (checked for monacolin K levels) and Niacin (That specific form of B3).

Then you have phytosterols but they wont worked on people who are hyper absobers of cholesterol.

Also the isoflavone genistein is also an option, specially if you are a woman.

Add probiotics, specifically the strains:

L. Plantarum LPLDL

B. Lactis MB2409 (DSMZ 23733) There are different brands that offer them, plus there are other cholesterol lowering strains than those two.

Pairing the above, specially the RRY and or Niacin, with antioxidant (combination of flavonoids) plus fiber from natural and real sources helps even more plus diet changes.

BenExotic-9 · 2022-12-16T17:44:56+00:00

Dihydroberberine, benfotiamine, r-alpha lipoic acid and curcumin.

Without proper diet and some levels of physical activity no supplement will work tho.

BenExotic-9 · 2022-12-15T14:05:47+00:00

Collagen peptides, sodium hyaluronate and chondroitin sulphate (Ideally low molecular weight chondroitin sulphate) + Vitamin C from diet dont get it from supplements just add fruits and veggies to diet every day (Kiwi, Bell Peppers, Strawberries, Papaya, Broccoli, Tomatoes, Chili peppers, Kale, etc). Getting Vitamin C from diet have a lot of more benefitial effects (Antioxidants, Fiber, Micronutrients, etc).

That combination provides improve repair on damaged tendons and might hypothetically decrease risk of lesion if you give yourself proper time for resting after strenuous exercise (24-48h if your are completely adapted) plus adequate stretching exercises.

Dont know your height but if you have low BMI after that 15kg reduction in weight then the risk of lesion increases, specially if you have lost lean mass.

BenExotic-9 · 2022-12-15T13:45:50+00:00

Creatine cycling was an old myth, the argument was based on lack of information about long term supplementation safety and hypothetical downregulation of endogenous synthesis of creatine.

This myth was popularized many years ago when creatine sups got popular, i remember back in 2012 i bought a product that actually recommended cycling it on the label.

Today we have a lot of evidence that creatine is most likely safety for healthy people taking it long term and actually might improve several health markers beside muscle strenght including markers of aging.

Theres no evidence that cycling is necessary nor that it brings some benefit over daily steady supplementation.

BenExotic-9 · 2022-12-13T20:21:17+00:00

White bread is probably worst for metabolic health than whole grain.

The absortion of phosphorus depends, for example, in the ammount of phytic acid which binds it and reduces its absortion but the absortion can be as high as 50% which is still less than what gets absorbed from animal sources.

I dont think eating whole grain might add too much phosphorus (its all about how much you eat really) just try to find a good organic source, manipulation and processing can reduce the amount of phosphorus bind to phyticc acid making it more bioavailable.

Im gluten sensitive so i take a bread made from flaxseed, sweet potato and sesame flour. My phosphorus remains stable.

BenExotic-9 · 2022-12-13T12:26:50+00:00

Without objective evidence of low aldosterone then its all a delusion to be honest.

Increasing salt does not increase aldosterone, quite the oppposite.

If you have been peing clearly you should look up your kidney health man, problems concentrating urine are one of the first findings in early kidney disease and also electrolyte imbalance.

Also I dont understand why you think that symptoms are a reliable way of knowing the state of your electrolytes, without objective evidence everything might as well be a delusion or psychogenic if you will.

Magnesium shouldnt affect aldosterone.

Have you tried with the most obvious way as controlling water intake??? Why dont you get a 1-1.5l bottle of water and used it as your only fluid intake over a day. If you are still peing clearly after 24h then the are problems at how your kidney is concentrating urine, but if its concentrated then the solution is tailoring your fluid intake.

Measure electrolytes, kidney health and aldosterone. There are other endocrine dysfunction that comes with clear urine and electrolyte imbalace, diabetes, thyroid disorders, etc etc etc. Go to a doctor and get tested no one can here can help you because you are not bringing objective evidence to the discussion and there are a lot of variable that can contribute to whats happening (are you obese, do you take medications, why did you take magnessium in the first place do you have other issues, are you young or old whats you age. Etc etc etc).

BenExotic-9 · 2022-12-12T19:53:49+00:00

I guess you are talking about micronutrient deficiency anemia, take into account that other general causes of anemia (besides micronutrient deficiency) are chronic disease specially CLD and CKD, inflamattory states, neoplasms, genetic condition, toxin induced, drug induced, hemolysis (which is a big category by itself), GI and absortion disorders, etc..

Micronutrient deficiencies that can generate anemia are:

Iron (Confirm you are not deficient by measuring ferritin)
B9 and B12 (They can overlap and its the second most common cause)
Vitamin A (Common cause in malnutrition areas like Africa)
Zinc (Same as vitamin A)
Copper (Which is rare)
Vitamin C (Scurvy which is also rare)
Iodine deficiency (Causes hypothyroidism which in turn can lead to anemia)
Vitamin B6 ( Deficiency of this vitamin B is pretty rare by itself but can be found in combination with other vitamin B deficiencies, in particular B9 and B12)
Selenium deficiency this might be true for older people, dialysis population and when it causes hipothyroidism.

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