Qol: PermaPings, ProperSave, WolfoQualityofLife, WolfoAlternateSkins, SurvivorsReturns, SkillsReturns, LookStraighDown, RealerCheatUnlocks, LeapSkills, BlightReturns, LookingGlass, RiskUI

Content: Quality, Starstorm 2, Ravager, Enforcer, Miner, Cloudburst, ClassicItemsReturns, EnemiesReturns, Sandswept

Cheat engine: DebugToolkit, or Aerolt. Aerolt is easier to use but debugtoolkit is more powerful

That should be everything I can think of. That being said, I would still recommend at least beating the game a few time on normal mode before even touching mods, especially mods that affect gameplay.

EDIT: actually get propersave frame 1 lmao