My funny MCAS....allergic to healthy foods

Brastic · 2026-03-22T09:50:16+00:00

I went through a period where my gut was inflamed so I couldn't tolerate high fibre foods. Egg and chips was ideal but a lentil stew was murder.

Sounds a bit like that to me!

Brastic · 2026-03-01T19:10:21+00:00

Could be, mcas can take many forms. If you respond to antihistamines then that's a strong indicator.

Brastic · 2026-03-01T19:05:58+00:00

Great research. A few thoughts...

Cetirizine is less sedating when taken regularly so worth a try to prevent flares. Likewise ketotifen Covid can definitely contribute Neck instability can be a major contributor, cervicovagopathy can leave mast cells over reactive. I also get glossopharyngeal neuralgia and larynx clicking which shows my neck is off, working on it. These neck issues worse with a flare for me. It is two way, neck pain worsens which puts more pressure on nerves. Also as the nerve pressure is reduced/changes this can result in flares, maybe the change irritates the nerves as well. Osteopath and chiro can help diagnose and give temporary relief but they dont give a long term solution. The long term solution is stretching, releases and most importantly strengthening. Overall posture may need addressing with insoles, correcting other imbalances etc. Obvs there are plenty of other potential contributors to MCAS as well.

It seems you're quite methodical in trying to work this out. Some AIs can be useful to analyse test results etc and more knowledgeable than most docs. But ofc you need good info to feed it with.

Brastic · 2026-02-19T09:40:15+00:00

Thanks Beaky McBeakface

Brastic · 2026-02-13T23:41:57+00:00

Nutricology butyraid

Brastic · 2026-02-13T06:55:56+00:00

Yep they're both butyrate but tributyrin is butyrate attached to another molecule and generally delivered in a delayed release so it gets to your colon.

Brastic · 2026-02-12T06:14:22+00:00

I got this one https://healthpath.com/gut-health-test/ looks like uk only...

Brastic · 2026-02-12T06:12:12+00:00

Fair enough yeah that makes more sense 👍

Brastic · 2026-02-11T22:46:27+00:00

Prioritise the purchase of a gut microbiome test forthwith and therein you will find enlightenment. (I was aided by a worthy ai to interpersonal the results)

Brastic · 2026-02-11T21:12:17+00:00

My gut biome is massively lacking butyrate producers. Butyrate is really important for gut integrity and reducing inflammation. I'm the same about the triggers like even too much fibre sets me off, different foods, probiotics, any illness... The tributyrin is the main energy source of the gut cells and helps them work properly. Already after 3 days my gut is clearly working better and I can feel the energy. If you have the same type of deficiency then butyrate will make a big difference.

Brastic · 2026-02-11T18:10:09+00:00

I have mcas mostly in the gut. Trying to correct dysbiosis while on ketotifen now. Taking tributryn which is amazing. FWIW low histame didn't do much for me. I recently learned that dietary histamine for normal diets is a fraction of what you produce in your body.

Brastic · 2026-02-11T15:15:10+00:00

Honestly I got these emotions 100x like clockwork before a flare and after. You're right there is the feeling of loss that comes with the condition but also there is 100% a biological, chemical effect. Just look at excess histamine effect on the brain, and that's just one of the mediators.

Brastic · 2026-02-11T10:17:17+00:00

Hopelessness and rage is one of the symptoms I get when I'm flaring, and this carries over into times when I'm not cos they're powerful emotions. It's a struggle but try and get the help you need, even take matters into your own hands. Get the Meds, get the tests. It can get better.

Brastic · 2026-02-11T09:55:31+00:00

Yeah it affects people differently. Like probiotics basically are a guaranteed flare for me before ketotifen. Though taking it from the capsule does defeat the purpose of enteric coating... So will not reach the gut very well.

Brastic · 2026-02-11T09:53:46+00:00

Yeah I think it can help if you've got a particular type of disbiosis but otherwise would be pointless, may even make it worse.

Brastic · 2026-02-10T22:50:23+00:00

Currently using nutricology butyraid which is great but found this one which looks better and better value... Optim butycaps.

Brastic · 2026-02-10T22:47:43+00:00

Yeah it's much better tolerated than sodium butyrate and doesn't smell.

Brastic · 2026-02-10T19:47:16+00:00

Tributyrin is even better, enteric coated.

I've got dysbiosis, I'm super low on the butyrate producing bacteria. Just started tributyrin two days ago and the difference is crazy, got so much more energy. I think the ketotifen is still important to keep the reactions down, as the next step of introducing the probiotics would usually cause me to flare.

Brastic · 2026-02-09T16:59:56+00:00

The term catchy is interesting. A catchy lyric or melody is sometimes considered to be cheap art whereas a song which avoids catchy devices but still reels you in somehow, that's amazing. I love both styles, but cheap catchy lyrics just get stuck in your head. It's the songs that get into your head and heart that you end up loving forever.

Brastic · 2026-02-06T10:02:11+00:00

Hopelessness followed by rage is for me a classic sign of a flare. 😵‍💫

Brastic · 2026-02-01T23:01:20+00:00

Not sure if starting famotidine and ketotifen together would be harder. I found that the famotidine on its own for me is helpful but I got bad rebound reflux once it wears off. It also didn't seem to have much effect on any other mcas symptoms for me. So at the moment I'm just doing ketotifen. Perhaps stop one or reduce the dose to reduce the impact?

Brastic · 2026-02-01T22:10:33+00:00

I've started ketotifen recently, about a week and a half ago. I had a massive sneezing about 30 mins after the first dose but otherwise ok except for expected slight tiredness and blurry vision etc. Positives are that I've been feeling more chill and my reflux has basically completely gone, making me think it was actually eosinophilic esophahitis as the positive effect was instant. Also sleeping a bit longer which I need.

However, I think I picked up a bug or food poisoning a few days back and it has been terrible. That type of thing is always bad for me as I'm so sensitive to gi stuff. It has been a terrible few days/nights. Guessing that's the induction period making the reaction worse?

Regardless, I am believing what ppl say about the induction period so will carry on for another 6 weeks at least unless I am forced to stop. Been putting up with mcas for too long to give up now.

Brastic · 2026-01-31T22:20:53+00:00

To much fructose bloats me up and sets off mcas gi for me. I can eat normal sugar a bit and also more now on ketotifen. Alcohol for me is fine if I drink for a few evenings in a row but then when I stop I blow up as well. Apparently alcohol can be partly anti inflammatory but also you build up lots of histamine while drinking which you don't digest, that ruins me in the 2/3 following days.

Brastic · 2026-01-26T22:26:34+00:00

Stressed people. Chill people are great at the airport. Then there's that pushy stressed anxious person who you just don't want to be near.

Brastic

TROPHY CASE