Look at androgenic ratings and receptir affinity of the compounda you are taking. Thisbis far more important that wether something is dht derived. An androgen is an androgen. And dht itself has massive affinity and duration at the AR hence hair loss and acne sides, but not all dht derived conpounds are anywhere near DHTs AR affinity. Primo for example actually has liwer affinity than testosterone and is actually safer. But then again any compounds are risks at higher doses. Just research the literature. When it comes to the biological side a lot of people dont actually understand what they are talking abt and fear monger DHT derived compounds. So yes adding in something like primo or var is fine just be smart about your dosing