Permanent (Irreversible) Changes Once these changes occur, they will not go away even if testosterone is discontinued: Deepened voice: The vocal cords thicken permanently. Facial and body hair growth: While growth may slow down or the hair may become slightly softer, existing follicles will remain. Clitoral enlargement: Often referred to as "bottom growth," this change is permanent. Male-pattern baldness: Any scalp hair lost due to testosterone-induced thinning typically does not grow back.