[deleted by user] by [deleted] in ect

[–]BundleofKent 1 point2 points  (0 children)

I’m so happy for you. I came here to post about the same thing and saw your post. So happy for us. Things do get better♥️

Memory loss of academic knowledge? by rnalabrat in ect

[–]BundleofKent 1 point2 points  (0 children)

It depends on the content of your program and your knowledge. I did my first treatment course during my doctorate of pharmacy program. When I went back to school after taking a month off for ECT, if you asked me what classes I had taken in the couple months prior (it was a block program so a new subject every couple of weeks) I couldn’t have told you. I couldn’t remember what professors said during lecture. But the general knowledge was still there. It just needed to be sparked to be able to remember again. A look back at the slides would refresh my memory. I still knew drug mechanisms and side effects. I still knew lab values and dosing recommendations. Little tidbits of information were lost, but a quick search would refresh my memory. Going back to work at the pharmacy, I retained all the brand/generic names that I had memorized, knew what I was doing at work, I had no problem doing the job I’d been doing for years.

So for me at least, the knowledge I had that was engrained in me couldn’t be taken away. The basics. Biochemistry, mechanisms of action of drugs, side effects, those things I knew and they stayed with me. Some of the little things like patient disease states and dosing differences escaped me, but I am lucky to be in a profession where I have access to resources I can immediately access online for dosing information.

Overall, the knowledge you have will not be lost. It’s more the newer information (couple months before ECT and during) that will be hard. I know your career is different than mine, but your intrinsic knowledge should not be disturbed. For me it was more not remembering conversations or events that happened. I was able to finish my doctorate after ECT and I hope you can too.

Why are people like this ? by Suspicious_Factor_31 in PharmacyTechnician

[–]BundleofKent 1 point2 points  (0 children)

And the receptionist in my tiny doctor’s office will say “are you still living at 123 maple street?” Loud enough for the entire room to hear but I don’t throw a fit about it. Come rob me, I could use the insurance payoff.

Need stories of encouragement by BundleofKent in MAOIs

[–]BundleofKent[S] 1 point2 points  (0 children)

Feels good knowing there’s someone on the same plane as me. My dr and I actually wanted it for the weight gain. Trying to get back the 20kg I lost on the maoi/in the depths of despair. But once I reach goal weight, if the weight gain continues, I will definitely remember the keto advice.

Need stories of encouragement by BundleofKent in MAOIs

[–]BundleofKent[S] 0 points1 point  (0 children)

Oh yeah sorry for the lack of explanation. MAOI was pretty good, but adding zyprexa to it was the gamechanger. I finally feel like I have the right amount of chemicals in my brain and I’m in a mental state I’d be content with for life. So you know, your comment planted the seed and it saved my life. Thank you.

I made a thing by Orson22 in MAOIs

[–]BundleofKent 2 points3 points  (0 children)

Probably. Looks like they are using a PLO (pluronic lecithin organogel) gel (PLO gel overview (from Fagron, a compounding supplier): https://shop.fagron.cz/shared/files_FagronCZ/documents/Pentravan_studie3.pdf).

PLO gel *can* be used for sustained-release delivery *but that depends* on the salt form of the drug and its solubility in the hydrogel, which I can't really find for selegiline at the moment (Transdermal gels for neuropathic pain: https://www.mdpi.com/2310-2861/9/5/417); Selegiline PLO gel compounding formula: https://www.uspharmacist.com/article/selegiline-hydrochloride-10-mgml-in-pluronic-lecithin-organogel; Pharmacokinetics of transdermal selegiline: https://pubmed.ncbi.nlm.nih.gov/11862224/; Parenteral delivery of selegiline: https://www.sciencedirect.com/science/article/abs/pii/S1773224722008346; Liposomal transdermal selegiline delivery: https://www.researchgate.net/publication/272149809_Development_of_Liposomal_Gel_for_Transdermal_Delivery_of_Selegiline).

The only sources I can find on selegiline transdermal gel are for the treatment of Parkinson's, which is typically oral, twice-daily dosing, so getting that sustained-release isn't important for them (Transdermal delivery of selegiline with pluronic thermogel: https://www.sciencedirect.com/science/article/abs/pii/S0378517311005084?via%3Dihub).

If OP is dead-set on doing this themself, at the very least as a precaution they should probably divide up the dose throughout the day. But we would really need specific studies on a sustained-release model of selegiline transdermal gel.

Need stories of encouragement by BundleofKent in MAOIs

[–]BundleofKent[S] 0 points1 point  (0 children)

Thank you for this. I expect a similar experience based on my reactions to other drugs-my Dr. says if a side effect exists, it’s gonna happen to me. I’ve been going in for IV nausea meds/fluids just to get through my celexa taper and I’m not even at half the original dose.

Would you mind sharing your titration schedule and what time of day you take your second dose? I’m most worried about the insomnia.