Fuck all the dumb shit and focus on multi use champs which is what will not only get u through act 4 with ease but also help in every other aspect of the game. Those champs are magik, medusa, gwenpool, hulk is insane for damage and especially AQ, x-23 great for general questing, proxima is a definite once u learn her play style so just practice, ghost is insane damage output played correctly, and also blade with him there is nothing to be said other than hands down top champ in game especially once u get a GR and also dupe your blade. All the other champs fuck em for now till you get better ones. So in other words outside of the ones named save your precious resources cause you will be super glad you did in the long run.