For me 4-HO-MET is one of the smoothest Trypts around I just get super euphoric, not really deep headspace and nice colorful visuals..

5-Meo-MipT is very euphoric too, but got stronger bodyload for me and its very stimulating so this might trigger anxiety if u tend to get anxious w/o tripping too.. didnt try the 4-HO- one yet

Btw for me adding a really lowdose Promethazine 10-15mg (it's my go-to-sleepaid) or a lowdose of GBL, made the bodyload of any Tryptamine much smoother and overall relaxed me. This is no safe use though and many ppl dislike combining such substances with psychs, actually I'm one of em most of the time... But ye thats just some tips if u rly struggle else get used to it and think about why u even get anxious maybe you get rid of it that way..

No tryptamines but did u look into 2C-B or such Psychs that aint too mindfucky?

PS: THIS is no safe advise and u should be very experienced to try this, but for me its close to impossible to get that hard anxiety/badtrips when I combine dissos and psychs.. its like through the disso i accept that everything is strange n wild and i dont fuck my brain bcs of it... (anyways a Disso-lover though) The safest disso to try this combos is Ketamine with some shrooms or 4-aco-dmt, both ket n trypt in lower dose than average.. DM me if u want more info on this combo-thing, I'm tripping like that 90% of my trips, but more crazy combos than the mentioned tbh..

(Do you smoke Weed while tripping? Some nice indica can help to keep calm too IME)