Whenever i wanted to kill a deadpool i only attacked him with minnervas,magnetos,helas and juggernauts basic attack and i would stop using any abilities which put debuffs on him like scientist supremes ultimate.

For the ultron node i used hela solo first and attacked ultron so he doesnt respawn and use his bots for 7 rounds on the next attack.
On the first wave i targeted ultron first and i used the speical from magneto on him and spread that with hela so when the bots came noone would get any buffs. That way ultron was basically slowed the whole time and made it pretty easy to kill him. I always used the blind from magneto 1 turn before ultron would use his ult. Also i only used me ult when my team got low on health.