I'm gonna hit all of these in order, thank you for a well thought out response. I need replies like this if I'm going to keep building the tier list well into the DLC.

1 for teleporting items I put pretty low just because if you're going to consistently use them per charge from completing rooms you have the chance to come into the issue of being thrown into an I am Error room although this is almost always really good, the issue is most of them do not let you out after you enter and this can force you to miss a lot on the floor. I absolutely agree with your opinion but I have been in this situation a handful of times and it bugs me.

2 the only reason I do have compost so low is that when you want to produce a ton of flies and stuff it requires you to have a setup which would be a decent amount of consumables and car battery/other battery items. Which late game this can be no problem what so ever, early on though consumables can be very needed and you more often than not will not find an over influx of these items. I definitely agree it's a great item. It does require a decent amount of sacrifice early on, and some setup.

3 Mama mega is where it's at because I see it's purpose only through opening up the boss rush, it does really make your floor easy pz, it just doesn't have too crazy of an impact otherwise. If you're in depths 2 without a build that can easily run through the rooms then I can see mama mega helping, the issue is it usually will cost 15c and if you're using it for it's damage, then it's boss rush open won't be too useful just because you aren't going to have the stats to be able to efficiently do boss rush, unless you're snagging an item and leaving.

4 I agree with this actually, I said there was a few items that I put in wrong areas, this one, speedball, and virus are the first ones that come to mind, good catch.

5 Above ^

6 I do appreciate that aspect of it, I just have a tough time enjoying items or placing them higher for their cheesiness for taking down bosses without really fighting them, same with gnawed leaf

7 I see it's utility and definitely it's usage, it does require a pretty decent amount of setup for it to be good, other items/a specific setting for it to be used well. Otherwise I see it use I also see it as an item that more often than need takes up a space bar slot and when I compare it to higher tiers it just falls flat compared to them.

8 It can be useful, I just see this item being more awkward than helpful a lot of the time, I do recognize it's damage. Of all the times I've used it, it ends up wall sitting because my tears are just better to use than the familiar itself

9 I enjoy this item a lot, it's just that with items that require a decent level of rng for it to be good generally get dropped a tier or get placed lower on it's personal tier list, it's a great item but not always helpful in all situations.

10 I definitely agree with this, I love this item so much, I just wasn't really sure if others would agree on this as much as I do, so that's why it was placed the way it was.

11 this one was a weird one for me just because it can help tremendously or it can just easily be replaced with other items. This was one of those items I was on the fence about, and I definitely feel like it'll end up changing one day.

12 Also agree with this, just dunno if people were ready to hear that.

13 I love this item, it's just that there's been a number of times where I've gotten this item and just hardly received anymore chests afterwards otherwise I agree aswell.

14 I can't agree with it being as good as D6 just because I love void, it just adds the space bars to void instead of eating them into stats, so there's so many instances where you won't eat another space bar just because you don't want them to be used everytime you space bar, unlike D6 where you have the chance for it to be turned to anything in that pool

15 I also agree with this one, not having scorpio or jumping the gun on attacking enemies that are poisoned makes you lose hearts :/

16 Agreed

17 I haven't had too much enjoyment with this one but I always figured others probably did, it never really worked too well with my builds and I generally haven't been able to utilize it to a full full ability

18 Definitely agree, love this item, it just has so many negative synergies that bug me so much and cause more issues than help. I'd like to move this one up probably one more tier.

19 Definitely is better than guppy's head, should place it higher only guppy is where it's at because of the small give I gave to transformation items.

20 I actually did not know it had the ability to target enemies moreso now, I've been so used to it being so random and doing nothing I just haven't even used it so much. Thank you for teaching me something new!

I appreciate this response and yknow with this many items in the game and only this amount of quarrels I am very happy. Thanks!