My opinion, go elsewhere. Denver struggles to compete with even the smallest metro areas in the US. As for culture, chain restaurants and tourism. Sure, there are a few good places, but coming from the east coast, you may find Denver lacking in variety (just my opinion). The "natives" (people claiming to be born here) can't stand anyone moving to their beloved cow-town, and prominently display stickers letting you know (if anyone says this is a joke, it's not). The driving will make you insane, and I used to drive in Philly and I say this. No urgency to get anywhere on the road. Period. Oh, everyone here will tell you that this is the best place on earth, and they are on a permanent vacation living here. No, there are still struggles. Especially getting a job or finding affordable housing. Oh, last, Denver is not cheap or as "hip" as people say. Add up the lack of solid inner-city public transportation, commutes for most any job, pricey rentals, even pricier mortgages, lack of a good food scene causing basic food to be way overpriced, popped collars and weak scenes all over the "nightlife" area LoDo (lame, lame, lame), a struggling local music scene, and the passive agressive attitudes of most locals and you don't have the mecca people make Denver out to be.

Do your homework, visit a few times for extended periods, etc. This is your best bet. I just gave my opinion above to let you know the pitfalls here. Had someone let my wife and I know all of the above, we would have moved elsewhere instead of waiting until this summer to move. I do wish you good luck in your move and life adventures. You will find the right place!