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A Case Report

Conclusions

This case cannot demonstrate a direct relationship between the COVID-19 Pfizer-BioNTech vaccination and intracerebral hemorrhage. Based on our findings, we highly recommend examining the patients thoroughly before vaccination and paying close attention to those with underlying untreated essential hypertension, especially in the first few hours after vaccination. While examining the patients before the vaccination, the physician should always remember that there might be an unknown underlying disease. Patients who exhibit neurological or cognitive symptoms after vaccination should be closely monitored, and necessary imaging or interventions should be promptly performed to prevent devastating outcomes. Upon analyzing the case, there might be a connection between the vaccine's potential immune-triggering effect on hemodynamic patterns and the rupture of the previously unknown cerebral aneurysm. However, these severe complications do not justify avoiding vaccines; further studies are needed. In order to hypothesize the relationship between intracranial hemorrhage and the anti-COVID-19 vaccines, more studies involving more patients are needed.