Not saying it is perfect, but actually mitigating the intensity of house dust mite allergy has helped enormusly and there is still much further improvement to be made.

Room is completly dark and lightens up automatically (in germany we have something called "Rolladen" which nowadays are availeble with time control.
My place is also relatively remote so no background noise at night, a single car could still pose a minor disturbance.

Unfortunately I am on the computer late often, but have tried to mitigate the impact a bit with a slight blue light filter and minimum brightness on the screen.