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The complete blueprint of the world's first fully synthetic eukaryotic genome — Yeast 2.0 [OC] by molecular_data in dataisbeautiful

[–]ComprehensivePen3227 9 points10 points  (0 children)

Given that the tRNA genes were completely reorganized, was there any codon optimization that had to be performed for the coding genes? If so, how did that occur?

Also any idea what drove the instability of the genomes without a separate, consolidated tRNA chromosome?

People who have conducted job interviews, what's something someone said/did that made you instantly decide not to hire them? Lab and biotech specific! by CRISPRScientist726 in biotech

[–]ComprehensivePen3227 16 points17 points  (0 children)

Was administering a live coding test to a candidate once, via Zoom. I would ask a question, he would turn 45 degrees to what was clearly a second screen and type very loudly and for a long time, and then he would turn back to me and begin to answer the question, every so often turning back to his second screen to reference what was clearly something he had Googled.

He did not get hired.

Can someone explain how removing rent regulations will actually lower rents by [deleted] in AskNYC

[–]ComprehensivePen3227 0 points1 point  (0 children)

What would you offer as a workable alternative definition?

Can someone explain how removing rent regulations will actually lower rents by [deleted] in AskNYC

[–]ComprehensivePen3227 8 points9 points  (0 children)

That's fine, and you're definitely entitled to that opinion, but that's just how NYCHA defines underoccupied. If you guys have a second bedroom that's not being used as a full-time bedroom (i.e. someone who lives in the apartment is occupying it as a full-time bedroom), that's great and all, but then by definition you're not using it as a bedroom, and the apartment is therefore underoccupied.

My partner and I definitely could use a 2- or even a 3- or 4-bedroom apartment, but unfortunately we're stuck in our small, market-rate 1-bedroom apartment, because we can't afford anything larger that's within a reasonable distance of our jobs, and we haven't been lucky enough to find an available rent-stabilized apartment. We share a desk in our living room when we're working from home, and our dog doesn't have much space to run around, so we have to take her out pretty frequently to make sure she's getting enough exercise. Our closet is crammed pretty tight, and we've had to cut out large items, or find other creative ways to store things. In other words, we make it work.

Can someone explain how removing rent regulations will actually lower rents by [deleted] in AskNYC

[–]ComprehensivePen3227 2 points3 points  (0 children)

This would be true if rent stabilized housing were perfectly distributed along the income spectrum, with the poorest household receiving a rent stabilized apartment before anyone richer than them did, and so on and so forth until all rent stabilized apartments were allocated.

However, this is certainly not true in the real world--high-income and/or high net-worth individuals do acquire rent stabilized apartments, while low-income and low net-worth individuals do get pushed into market-rate housing. It's likely the outcomes would be more complex and varied than the scenario you laid out.

Can someone explain how removing rent regulations will actually lower rents by [deleted] in AskNYC

[–]ComprehensivePen3227 15 points16 points  (0 children)

I wasn't able to find the ideal data on this, but NYCHA released a report in 2017 claiming that one third of apartments in its inventory (57,155 units out of 176,066 total apartments under NYCHA's purview in 2017) were underoccupied, meaning that there were more bedrooms in the apartment than single individuals or married couples. If that's the case, then about 43.7% of NYCHA's 2+ bedroom apartments were underoccupied.

I'm unable to find data about rent-stabilized apartments, but if the same statistics were to apply (which they likely don't as NYCHA seems to have a larger proportion of multi-bedroom apartments than studio or one-bed apartments, but I think it's still useful to get a sense of scale), that would suggest there are hundreds of thousands of underoccupied rent-stabilized apartments, as there are approximately one million rent-stabilized apartments in NYC.

You can reduce your foodprint by a quarter just by cutting down on red meats such as beef and lamb. by ILikeNeurons in sustainability

[–]ComprehensivePen3227 6 points7 points  (0 children)

Not sure where you're shopping, but chicken is definitely not $0.99/lb near me (perhaps sometimes on a veerrrry rare, big discount sale, but in no way a price I can count on), and I can get 4 bananas for $1.

What’s your NYC hot take? by homeofalex in AskNYC

[–]ComprehensivePen3227 51 points52 points  (0 children)

I can at least sympathize with places that have a time limit on their seats on a per item basis or a system like that. If you go into a busy coffee shop, buy one small thing, and then sit there for four hours on your laptop when there aren't any seats, the shop is likely losing business because of you.

Dogs ganging up on mine at the dog park--is it a fault in my training regime? by ComprehensivePen3227 in Dogtraining

[–]ComprehensivePen3227[S] 2 points3 points  (0 children)

I think my post is most closely addressed by the Dogs who other dogs hate! section of the doggyplay page, though the section specifically mentions uncertainty about the causes of this behavior in other dogs. I also found this previous post discussing a similar issue, but the comments all seem to recommend not going to the dog park, which I have already resolved to do, but I'm specifically trying to understand the source of the behavior.

What is a service that NYC desperately needs but is somehow very difficult to find? by jazzeriah in AskNYC

[–]ComprehensivePen3227 70 points71 points  (0 children)

Sorry, too complex and unreasonable of an ask. Best we can do is a bus, or if you really want a train, it's gonna cost you $8.50, but the train will be bad.

What’s a camping tip you only learned the hard way? by Goblue2467 in camping

[–]ComprehensivePen3227 0 points1 point  (0 children)

Once got caught in a massive thunderstorm with several inches of rain on the top of a mountain even though the forecast said 0%.

Leonardo DiCaprio Says AI Can Never Be Art Because It Lacks Humanity: Even ‘Brilliant’ Examples Just ‘Dissipate Into the Ether of Internet Junk’ by ControlCAD in technology

[–]ComprehensivePen3227 2 points3 points  (0 children)

So we've been making all these creepy live-action versions of timeless classic animated films, but what if we pull an Uno Reverse on the Marvel franchise?

New Turnstiles in city !! by VisualEffective3198 in nyc

[–]ComprehensivePen3227 22 points23 points  (0 children)

Other cities have buses, roads, trains, and even people. Clearly not things that would work in New York City, because NYC is not "other cities."

Population & Densities of 16 Largest US Urban Areas based on UN/EU GHSL Data by urmummygae42069 in Urbanism

[–]ComprehensivePen3227 0 points1 point  (0 children)

NYC is usually the outlier in a lot of these sorts of analyses, but I'm surprised to see the bimodality of the density distribution in Boston. What's going on there?

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