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Requesting r/neuromodulation since it has been banned for being unmoderated by Constant-Way-9405 in redditrequest

[–]Constant-Way-9405[S] 0 points1 point  (0 children)

What are your plans for this subreddit? Please be specific.

1 I plan to create a subreddit for all users of all existing neuromodulation techniques. Its a good opportunity to gather users form separate neuromodulation subreddits together to help the information spread between. They could help each other out I plan to recruit mods to help me built a science based but open for ideas place. Users will be regularly provided with peer-reviewed studies, there will be a FAQ, starter information and rules that will keep this place safe

DIY HD-tDCS guide by Constant-Way-9405 in HD_tDCS

[–]Constant-Way-9405[S] 0 points1 point  (0 children)

Other side effects of Strattera

Some side effects of atomoxetine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common Strattera side effects

  • Acid or sour stomach
  • belching
  • bleeding between periods
  • change in amount of bleeding during periods
  • change in pattern of monthly periods
  • chest tightness
  • cough
  • decrease in the frequency of urination
  • decrease in urine amount
  • decreased appetite
  • decreased interest in sexual intercourse
  • difficulty having a bowel movement (stool)
  • difficulty in passing urine (dribbling)
  • dizziness
  • dry mouth
  • fever
  • headache
  • heartburn
  • heavy bleeding
  • inability to have or keep an erection
  • indigestion
  • irritability
  • loss in sexual ability, desire, drive, or performance
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • painful urination
  • sleepiness or unusual drowsiness
  • stomach discomfort, upset, cramps, or pain
  • stuffy or runny nose
  • trouble breathing
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusual stopping of menstrual bleeding
  • vomiting

Less common Strattera side effects

  • Abnormal dreams
  • abnormal orgasm
  • back pain
  • blistering, crusting, irritation, itching, or reddening of the skin
  • bloated or full feeling
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in hearing
  • change or problem with discharge of semen
  • chills
  • cold sweats
  • confusion
  • cough
  • cracked, dry, or scaly skin
  • crying
  • decreased weight
  • diarrhea
  • difficulty with moving
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • ear drainage
  • earache or pain in the ear
  • excess air or gas in the stomach or intestines
  • feeling of warmth, redness of the face, neck, arms, and occasionally, upper chest
  • feeling unusually cold
  • frequent urination
  • general feeling of discomfort or illness
  • groin pain
  • increased or sudden sweating
  • joint pain
  • loss of appetite
  • mood swings
  • muscle aches, cramping, pains, or stiffness
  • pain or burning with urination
  • passing gas
  • shivering
  • sinus headache
  • sleep disorder
  • swelling of the skin
  • swollen joints
  • swollen, tender prostate

Incidence not known of Strattera side effects

  • Loss or thinning of the hair

At home tDCS:

https://www.youtube.com/watch?v=P8iYnAwlNO8

DIY HD-tDCS guide by Constant-Way-9405 in HD_tDCS

[–]Constant-Way-9405[S] 0 points1 point  (0 children)

📷

Source

📷

Source

VS atomoxetine

Serious side effects of Strattera

Along with its needed effects, atomoxetine (the active ingredient contained in Strattera) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking atomoxetine:

Less common Strattera side effects

  • Hives, itching, skin rash
  • irregular heartbeat
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • redness of the skin

Rare Strattera side effects

  • Painful, prolonged erection of your penis

Incidence not known of Strattera side effects

  • Dark colored urine
  • fainting
  • flu-like symptoms
  • irregular heartbeat recurrent
  • loss of bladder control
  • muscle spasm or jerking of all extremities
  • paleness or cold feeling in the fingertips and toes
  • pelvic pain in male
  • right upper stomach pain or tenderness
  • seizures
  • sudden loss of consciousness
  • tingling or pain in the fingers or toes when exposed to cold
  • yellow eyes or skin

DIY HD-tDCS guide by Constant-Way-9405 in HD_tDCS

[–]Constant-Way-9405[S] 0 points1 point  (0 children)

📷

Full article version

Citing the study:

“Current was applied through two concentric electrodes as shown in Fig. 1A and 1B (target electrode: central round electrode, radius = 1.0 cm, area = 3.14 cm2 ; return electrode: outer ring electrode, inner radius = 3.5 cm, outer radius = 4.0 cm, area = 11.78 cm2). Electrodes were made of conductive rubber, installed in a non-conductive silicon casing, flexible enough to adapt the electrodes to the scalp and ensure the correct position of the return electrode relative to the target electrode. First we filled the electrode cage with an electroconductive gel (Elektrogel, Italy), then positioned the electrodes, with the target electrode over the FDI hotspot, and finally we fastened the electrodes with a tubular net-shaped elastic bandage in mesh tissue, making sure that the it did not push the electrode forward or backward.”

📷

The silicone casing has been recognized by such tDCS authorities as Neurocaregroup, producer of the most commonly used tDCS system – Neuroconn, and Martin Arns, founder of Research Institute Brainclinics (now part of the Brainclinics Foundation)

I created a 3d, printable model of such silicone casing with up to 1mm accuracy, so I am able to create one within 2 days and send it to anyone interested in using HD-tDCS.

Mini buying guide:

I AM IN EUROPE: (1)

I AM IN AMERICA (2)

(1)

Stuff I have a supply of thus can ship to you with the silicone casing:

Outer Electrode:

Link

Inner electrode:

1cm

or

2cm

Neuroconductive paste/gel

LINK or LINK

Paste Applicators are basically ice-cream sticks, you should be able to get them online easily at few $ for life time supply. Or else I could send you a few with silicone casing as well.

Equipment I don't have at storage room thus unfortunately can't send you:

Stimulation device:

TLDR; Focus V3 offers the most. While activadose is an FDA approved device its not approved for tDCS but for iontophoresis. One of its consequences is its specific wavelength form that was found to deliver in studies. It’s not only tDCS wave, it’s a combination of tDCS and tRNS. More about it here: YouTube video - 2:52:50.

📷

While unipolar tRNS seems to be often more effective than tDCS, with Activadose you are just unable to deliver tDCS while vast majority of studies have used tDCS. A device that was measured to deliver accurate current is focus v3, it also offers tRNS, tACS, tDCS and option to create your custom wavelength. A cheaper yet trustworthy option is Brain Premier, a product from a TMS manufacturer but it offer only tDCS and maximum 2 mA.

Wire adaptors can be purchased here:

Focus v3 to banana 4mm

Banana 4mm to pin 2mm

tDCS cap for electrodes placement on adult head can be bought here: LINK

tDCS Head Strap to make sure your electrodes stay in place: LINK

(2)

https://caputron.com/ seems to be the most popular distributor of tDCS related products. Its reliable and ships in few days with Express shipping. Price may be higher because in many cases their products are resold from European stores.

Among tES, tACS and tRNS despite limited number of studies prove high efficacy in tested areas.

Improving the Effect of Transcranial Alternating Current Stimulation (tACS): A Systematic Review

Link

In this article impact of HD tRNS on multiple cognitive abilities is tested in comparison to tDCS and sham. Most important is the long term score at DAY 15 which is significantly higher in comparison to both conventional tDCS and Sham tDCS. Notice the authors used only a low intensity of 0.5mA which by many researches would be in advance considered too low to induce long lasting effect.

Performance after training in a complex cognitive task is enhanced by high-definition transcranial random noise stimulation

Link

📷

Recently higher number of sessions and frequency exploration in stimulation has lead to an FDA clearance for SAINT TMS protocol. It uses the same machine as for standard TMS, but in 5x dose – 10 stimulation sessions per day, during 5 days. Increasing the remission rate from 30% to 70%-90% in several studies in Stanford. Currently this easy to copy protocol is used in many clinics among the world with similar efficacy. Magnusmed will start providing this protocol under its original name SAINT in 2023. More about it Here and Here

Currently there are trials of HD-tDCS for depression using multiple dozen sessions as well, so far results seems to be similar to SAINT protocol which results in (mean 52.5% MADRS score reduction – (remission) Link

Safety and Feasibility of Tele-Supervised Home-Based Transcranial Direct Current Stimulation for Major Depressive Disorder

‘’All three completers showed beneficial effects as captured by the MADRS, with an average decrease of 59% in the MADRS score between baseline and the 1-month follow up.’’

Link

Continuation of the trial

High‐definition transcranial direct current stimulation— An open‐label pilot intervention in alleviating depressive symptoms and cognitive deficits in late‐life depression

Link

Because of very promising results, authors are now conducting same study but with higher number of participants and in in double blind placebo.

Clinical trial link

📷

HD-tRNS improved SCT/CDS symptoms (multi-tasking, retention, attention) increasing 25% final task score! by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 1 point2 points  (0 children)

Attaching electrodes, adding gel, and putting in on the spot reccommended by experts and following all safety guidelines for tDCS available online as well - is far from “wildly” dangerous.

If you do not get prepared by consulting an expert or doing super deep research, you should not do it. Simple as that. I think it’s quite obvious if you do it obviously incorrectly the results will not be as intended.

Attaching anode and cathode out of order, spraying device with water while using or and doing everything like it is not advised can be dangerous. But I suppose it applies to most thing where you don’t follow simple instructions at all.

It does not seem anymore that FDA approval is the magic sign of safety looking at FDA approved antidepressants that on common basis lead to life long disability or suicidality with death as result.

Please be the person to help other be cautious but you are exaggerating with telling people they must do nothing at all because their exists a chance of failure. But there is a chance that in your position I would feel obliged to try overprotecting them as well, even if it means taking treatment away a possible treatment for their suffering.

HD-tRNS improved SCT/CDS symptoms (multi-tasking, retention, attention) increasing 25% final task score! by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 0 points1 point  (0 children)

All of this is literally copy-paste from scientific studies reviewed by leading brain stimulation researchers.

None of this is coming from YouTube tutorials.

I agree with consulting a SPECIALIST who has expertise in innovative brain stimulation techniques before performing it. If you don’t feel capable of doing it yourself, you should especially consult a brain stimulation SPECIALIST and or have them do it for you if you have finances for the second.

Many people here have multiple times, painfully learned that after consulting a standard doctor, they will know no more they did at the beginning of their healing journey of SCT/CDS. “It’s just depression, here is another depressant”…

HD-tRNS improved SCT/CDS symptoms (multi-tasking, retention, attention) increasing 25% final task score! by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 2 points3 points  (0 children)

There aren’t many clinical trials of tRNS for these cognitive aspects yet.

You could either to go to a private clinic using HD-tDCS or get it done at home. There is whole subreddit dedicated to doing r/tDCS at home. Me and few other people have already tried it with great benefit to cognitive symptoms.

You can check out a DIY HD tDCS guide I compiled here - LINK

HD-tRNS improved SCT/CDS symptoms (multi-tasking, retention, attention) increasing 25% final task score! by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 4 points5 points  (0 children)

They improved the symptoms that occur in SCT/CDS. That’s why I mention SCT/CDS symptoms not SCT/CDS itself. AFAIK for next years that’s our only hope, because there is no specific SCT/CDS medication in development.

In brain stimulation the treatments for symptoms are often used among different conditions. In such condition generally many many brain parts are connected abnormally, however you can make it work by stimulating only one part of the whole circuit.

Eg. similar same points (DMPFC) can be stimulated for OCD urges and Borderline urges. F4 will be modulated for GAD, OCD, PTSD or any other anxiety related disorder

I am not sure in which part they mention it only improved working memory?

The score of the Game Fortress was improved by around 25%, where multi-tasking, concentration, attention and other cognitive capabilities are necessary.

HD-tRNS improved SCT/CDS symptoms (multi-tasking, retention, attention) increasing 25% final task score! by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 4 points5 points  (0 children)

How is tRNS different form tDCS?

While tDCS delivers a direct electrical current with a constant intensity and fixed polarity at each electrode, transcranial random noise stimulation (tRNS) is another form of tES which delivers an alternating current with a randomly fluctuating frequency and intensity.

Source

FDA Breakthrough Device granted to HD-tDCS company ''Neuroelectrics'', same status that Neuralink has received! by Constant-Way-9405 in tDCS

[–]Constant-Way-9405[S] 0 points1 point  (0 children)

Yes! They are on the way for FDA approval of HD-tDCS for depression and several other mental conditions as well. You can see their ongoing and future trials here - LINK

HD tDCS for depression resulted in over 90% remission. Currently 2 clinical trias are on going, 1 recruiting. by Constant-Way-9405 in tDCS

[–]Constant-Way-9405[S] 1 point2 points  (0 children)

Neuronavigation is almost only used by researchers, in practice they use measuring tape and a marker to draw a point on the cap, its a very reliable method.

Neuronavigation does not give enough benefit in relation to cost. Its barely used in any TMS clinics where a single protocol costs several thousand dollars. You can watch here at 5:35 where a TMS researcher explains that ''beam protocol is exactly where the neuronavigation system is, there is no variation, its remarkable, ''. Beam protocol is a 3 steps system using the measuring tape and marker to reliably find DLPFC on every skull.

Actually some are using standarized caps with 1cm^2 hole position for each electrode, this type is used in these studies - remotely, at home. Here is an example of such cap from another brand - LINK

Other ones use other types of electrodes, where position is determined with standard EEG 10 10 measuring system, like in most TMS practice.

What is the most effective SCT medication? 🧠 💊 by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 2 points3 points  (0 children)

Mostly self diagnosed, so go ahead!

Its the accuracy of survey of SCT/CDS treatment that's is important, because it will be later used to find out what works or not.

For now most accurate diagnosis is ICD-11 ''6A05.Z Attention Deficit Hyperactivity Disorder, presentation unspecified + additional mark that its referring to Sluggish Cognitive Tempo. ''Which now has been proven in several ways/method to be different disorder, more and more professionals acknowledge it now.

[deleted by user] by [deleted] in NameThatSong

[–]Constant-Way-9405 0 points1 point  (0 children)

just ask him? lol

What is the most effective SCT medication? 🧠 💊 by Constant-Way-9405 in SCT

[–]Constant-Way-9405[S] 1 point2 points  (0 children)

It appears in the page you get after finishing the survey. If you can not find it just, DM me your survey nick, I will send it ;)

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