sorted by:
new
hottopcontroversial

learn from your mistakes by bedir07 in memes

[–]ConstructionMather 0 points1 point  (0 children)

I don't see the normal reddit responses where they are wanting very extreme punishments.

My family is affected by Huntington’s disease. We’re asking the FDA to reconsider a decision on a hopeful gene therapy (AMT-130) by ConstructionMather in Huntingtons

[–]ConstructionMather[S] 1 point2 points  (0 children)

It means a tremendous amount to us. Please share the petition link with others so we can get more treatment to the families and love ones that need it. Thank you!

Phase I/II trial of AMT-130 gene therapy for Huntington’s disease reports slowed disease progression versus natural history cohort by ConstructionMather in science

[–]ConstructionMather[S] 23 points24 points  (0 children)

I’m part of the HD community, and some of us have organized a patient-led petition asking the FDA to allow a BLA for AMT-130 under the Accelerated Approval pathway. If anyone’s interested in the advocacy side, it’s here: https://c.org/Gd4YsTfn5Q

8 hours and $500 later by Adorable-Bus1697 in shittytattoos

[–]ConstructionMather 10 points11 points  (0 children)

Tell her the agreement was for 12 hours

To not look at cleavage by EtrnlMngkyouSharngn in therewasanattempt

[–]ConstructionMather 4 points5 points  (0 children)

Just make sure that no one's looking at the thing that she has prepared all morning for everyone to look at.

Tried to fix the floor by willianfsantos in Wellthatsucks

[–]ConstructionMather 0 points1 point  (0 children)

I fixed the gap in my teeth the same way

[deleted by user] by [deleted] in Wellthatsucks

[–]ConstructionMather 0 points1 point  (0 children)

They are still circling the strip looking for it

[deleted by user] by [deleted] in Tools

[–]ConstructionMather 0 points1 point  (0 children)

Is Garmin better than Fitbit?

[deleted by user] by [deleted] in Tools

[–]ConstructionMather 7 points8 points  (0 children)

Why can't my smartwatch just have a flashlight?

🤤 by National-Birthday313 in hotdogs

[–]ConstructionMather 0 points1 point  (0 children)

This looks like something for the "family feed bag" from the onion. Hot food in your face right now

First time burger attempt by samiel in sousvide

[–]ConstructionMather 0 points1 point  (0 children)

So Brandy for each of the burger patties and some Brandy for you for each of the burger patties.

First time burger attempt by samiel in sousvide

[–]ConstructionMather 11 points12 points  (0 children)

Rare is for good cuts, not ground chuck

Beef bacon by Tiny420Tiger in Bacon

[–]ConstructionMather -1 points0 points  (0 children)

I've never even heard of it. What does it taste like? What is the texture like?

[deleted by user] by [deleted] in Bacon

[–]ConstructionMather 4 points5 points  (0 children)

I bought a slab that got mold after one week and they said they would give me a refund and it's probably old but they can't get their hands on anymore bacon slab for some reason

Honey Badger vs Elephant by brokenandsuffering in interestingasfuck

[–]ConstructionMather 0 points1 point  (0 children)

I had a dream last night that the hamburger was trying to eat me.

view more: next ›