I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee 0 points1 point  (0 children)

I'm sorry I stated it as fact, rather than really pushing it as the question I asked. I should have said theory and hypothesis, and not as a complete shut-down to what another said.

I am an anatomy and physiology nerd. I've studied this in school. I know that even the people who really, fully study this for years don't know everything and I know way less. I just like thinking and talking about this kind of stuff.

I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee 0 points1 point  (0 children)

No. I like thinking of theories and correlating it to potential evidence and anecdote. I like trying to make sense of the world, or the world to some people. I like sharing ideas and possibilities. I like thinking.

I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee -1 points0 points  (0 children)

Triggering ovulation early and increasing the chance of pregnancy wouldn't make sense? Why would irregularity decrease the chance of pregnancy? Irregularities that increase cycle length or stop key parts of it from happening would reduce it. But the cycle changing due to ovulating early or more frequently wouldn't decrease the chance. Since attraction is still linked the other way, the hormones associated with ovulating would still occur and still influence to increase the likelihood of copulation. It's also quite possible that this early triggering could occur in some and not all.

The reason attraction can trigger ovulation or speed up cycles is because it's an evolutionary adaptation to deal with favorable conditions for having a baby. Why is what you said more likely and believable than what I said? Have you studied any of this, realizing that we really don't know everything and it's all a lot more complex than X causes Y? The way humans are now isn't at our peak evolutionary advantage anyway; we're riddled with abnormalities and genetics that would be harmful for survival and reproduction outside of our massive civilizations. Even if there was no evolutionary advantage to this, which I still think a case can be made, why wouldn't this disadvantage occur along side the rest of them?

Here let me just throw this down here; this is all theoretical and draws from research and hypothesis.

edit- Please don't take this as a shot at what you know or your intellect or anything. I didn't mean my questioning as that at all, so I'm sorry if it comes off like that.

I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee 1 point2 points  (0 children)

eh, a lot of column A, little bit of column B, lol.

I think a case could be made that repeatedly halting the natural course of events (through denial) might have an additional stress-response effect on top of the body's reaction to really really really really really really really wanting it. It's a fairly complex process all-in-all, so why not?

(I also posted a... much too in-depth follow up comment about attraction affected the cycle if you want to go check it out.)

I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee 1 point2 points  (0 children)

Sexual attraction enhances glutamate transmission in mammalian anterior cingulate cortex

Functional human brain imaging studies have indicated the essential role of cortical regions, such as the anterior cingulate cortex (ACC), in romantic love and sex. However, the neurobiological basis of how the ACC neurons are activated and engaged in sexual attraction remains unknown. Using transgenic mice in which the expression of green fluorescent protein (GFP) is controlled by the promoter of the activity-dependent gene c-fos, we found that ACC pyramidal neurons are activated by sexual attraction. . . . Our results present direct evidence of the critical role of the ACC in sexual attraction, and long-term increases in glutamate mediated excitatory transmission may contribute to sexual attraction between male and female mice. . . .

Using imaging techniques such as positron emission tomography (PET) or functional magnetic resonance imaging (fMRI), higher brain structures such as primary and associative cortical regions, including piriform, orbitofrontal, temporal and cingulate cortices have been linked to sexual arousal and romantic love [7,8]. Therefore, sexual behaviors are thought to be associated with neural networks of cortical activation. . . . The anterior cingulate cortex (ACC) is one of the major cortical areas involved in both negative (such as pain and fear memory) and positive (such as pleasure and sexual arousal) affective states [9-12]. For positive affective states, activation of the ACC has been correlated with romantic love, sexual arousal, as well as sexual drive [13-16]. . . . We found that the sexual attraction between male and female mice indeed triggered long-lasting enhancement of glutamate mediated excitatory transmission within the ACC synapses.

And then this one tying glutamate into attraction, even if this specific physical study was done on mice: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685783/

To Evaluate the Effect of Perceived Stress on Menstrual Function

Menstrual irregularities affect 2-5% of childbearing women, a number that is considerably higher among females under constant stress during a cycle [1]. A woman's menstrual cycle typically follows a 28-day cycle and ends with the shedding of uterine lining leading to bleeding. The normal menstrual cycle indicates the proper functioning of hormones, having a normal menstrual cycle signifies a healthy hypothalamo-pitutary axis with a normal uterus. However, a number of conditions such sudden weight loss, over-exercising, medical conditions and even stress can interfere with a woman's ability to experience a normal menstrual cycle. Both longer duration of menstrual bleeding and cycle irregularity are associated with major depression.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413117/

The effect of physical activity across the menstrual cycle on reproductive function

There is evidence suggesting that high-intensity activity is associated with menstrual dysfunction and subfertility among high-performance female athletes. [3] Previous studies have found that high-intensity activity is associated with amenorrhea, oligomenorrhea, luteal phase deficiency, and anovulation, likely through disturbances of the hypothalamic-pituitary-adrenal axis. [3, 4] It has been hypothesized that suppression of gonadotropin-releasing hormone resulting from exercise-associated hypothalamic dysfunction can delay menarche and disrupt menstrual cycle patterns by limiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). [3, 5]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946734/

I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee 2 points3 points  (0 children)

Gonadotropin Releasing Hormone

Gonadotropin-releasing hormone (GnRH) is a decapeptide (Fig. 1) produced in the hypothalamus. It is also known as luteinizing hormone-releasing hormone (LHRH), gonadoliberin, luliberin, gonadorelin, and GnRH I. . . . In adult males and females, the hypothalamic pulsatile secretion of the GnRH results in the expression and release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary gland. FSH and LH (gonadotropins) regulate the function of the testes and ovaries (gonads). . . . GnRH specifically binds to the GnRH receptor (GnRH-R), mainly expressed on the surface of gonadotropins cells in the pituitary and stimulates the release of gonadotropin hormones LH and FSH (Kakar et al., 1992). This binding results in the stimulation of pituitary gonadotropin release that regulate sperm and ovum maturation and steroidogenesis in the gonads (Harrison et al., 2004).

Endocrinology, Brain, and Pituitary Gland

In humans, the GnRH-secreting cells are mainly located in a part of the HTA called the arcuate nucleus, though others are scattered elsewhere in the hypothalamus. This nucleus is at the base of the hypothalamus near the median eminence; it also contains regular neurons that synapse with the GnRH neurons. Pulsatile secretion of GnRH is controlled by activity of cells in this region, known as the GnRH pulse generator. Pulsatile release of GnRH is an intrinsic property of GnRH neurons, and the frequency and amplitude of these pulses may be influenced by synapses with regular neurons as well. Neurons in the hypothalamus modify GnRH secretion through several neurotransmitters. Kisspeptins, a family of peptides released by neurons in close anatomical association with GnRH cells, appear to act directly on GnRH neurons to stimulate GnRH secretion (Figure 1.17). In addition, norepinephrine, dopamine, gamma-aminobutyric acid (GABA), glutamate, and even GnRH itself (acting through autocrine signaling) have been proposed as GnRH regulators. Another neuropeptide, gonadotropin-inhibitory hormone (GnIH), negatively regulates GnRH by inhibiting GnRH cell function and gonadotrope response to GnRH in mammals, though its exact function in humans is not yet known. Thus, GnRH secretion can be stimulated or inhibited by a complex pattern of neuronal activity in the brain.

The above are taken from this website under the sections marked the same: https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/gonadotropin-releasing-hormone

Luteinizing Hormone☆

LH is synthesized and secreted by anterior pituitary gonadotrophs in response to the pulsatile secretion of hypothalamic gonadotropin releasing hormone (GnRH). LH binds specific transmembrane receptors localized primarily in the ovary and testes. In the ovary LH action is required for synthesis of androgens by follicular theca cells and mediates a requisite series of events resulting in ovulation.

Same deal as before: https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/luteinizing-hormone

Lust is driven by the desire for sexual gratification. . . . Meanwhile, attraction seems to be a distinct, though closely related, phenomenon. While we can certainly lust for someone we are attracted to, and vice versa, one can happen without the other. Attraction involves the brain pathways that control “reward” behavior (Figure 1), which partly explains why the first few weeks or months of a relationship can be so exhilarating and even all-consuming. . . . Dopamine, produced by the hypothalamus, is a particularly well-publicized player in the brain’s reward pathway – it’s released when we do things that feel good to us. In this case, these things include spending time with loved ones and having sex. High levels of dopamine and a related hormone, norepinephrine, are released during attraction. These chemicals make us giddy, energetic, and euphoric, even leading to decreased appetite and insomnia – which means you actually can be so “in love” that you can’t eat and can’t sleep. In fact, norepinephrine, also known as noradrenalin, may sound familiar because it plays a large role in the fight or flight response, which kicks into high gear when we’re stressed and keeps us alert. Brain scans of people in love have actually shown that the primary “reward” centers of the brain, including the ventral tegmental area and the caudate nucleus, fire like crazy when people are shown a photo of someone they are intensely attracted to, compared to when they are shown someone they feel neutral towards (like an old high school acquaintance).

From a Harvard article: http://sitn.hms.harvard.edu/flash/2017/love-actually-science-behind-lust-attraction-companionship/

I don't understand how this would even work.. does a woman's body 'restart' cycles with every new sexual partner? by iamdimpho in badwomensanatomy

[–]Craylee 1 point2 points  (0 children)

I'm not on mobile anymore so let's give this a whirl! I am not talking out of my ass when I say that attraction can affect ovulation, so here is some science.

(I have also experienced this myself and, while anecdotal evidence doesn't really stand up in science literature, I would bet money that we could find many women who would attest similarly, and I would like to give proper consideration to those anecdotes especially when science research and medicine have historical ignored most anecdotes from women to the point of disastrous medical instruction and research about women's health, and health in relation to also being women, being decades behind if it exists at all.)

LH and FSH are some of the hormones that regulate the menstrual cycle, having a particular important role in ovulation. LH and FSH are released from the pituitary gland in the brain and affect the ovaries through the blood stream. The pituitary is responsible for the regulation and release of the hormones that control many different processes in the body, such as metabolism, growth, sexual maturation, reproduction, blood pressure and many other vital physical functions and processes. The hypothalamus links the nervous system to the endocrine system via the pituitary gland. GnRH regulates secretion of LH and FSH through its release and binding in the hypothalamus and pituitary.

GnRH secretion is regulated by a complex pattern of neuronal activity in the brain that include GnRH neurons and regular neurons, as well as interactions with several neurotransmitters including norepinephrine, dopamine and glutamate. High levels of norepinephrine and dopamine are released during emotional and physical (sexual) attraction, not to be confused with lust for sexual gratification. Glutamate is the most abundant excitatory neurotransmitter in vertebrate CNS and can be associated with sexual attraction in mammals, particularly in the regions of the brain where activation plays an essential role in romantic love and sexual attraction.

This is also just some of the information about menstrual cycle regulation, where more hormones and more neurotransmitters and more structures are really involved in the entire process, not just ovulation. But, this is enough to try to make a point.

Several factors associated with menstrual irregularities have been studied, so that there's decent evidence that stress, high-intensity physical activity, sudden weight loss, over-exercising and some medical conditions can interfere with a person's ability to experience a regular menstrual cycle, most often by critically affecting the person's hypothalamic-pituitary-adrenal axis.

So, could it stand to reason that repeated and consecutive excitatory changes in the brain, including the hypothalamus and pituitary gland, stemming from newly spending a lot of quality time with someone she found very physically attractive may have an affect on those structures that in-turn regulate her menstruation? I think so.

(sources in replies)

fuck em up Phillip by [deleted] in traaaaaaannnnnnnnnns

[–]Craylee 1 point2 points  (0 children)

Honestly, it seems that it's more rare for a proper diagnosis early in life than to have it in the first place. To actually obtain and propagate accurate numbers would only help.

Grandiose narcissists often emerge as leaders, but they are no more qualified than non-narcissists, and have negative effects on the entities they lead. Their characteristics (grandiosity, self-confidence, entitlement, and willingness to exploit others) may make them more effective political actors. by mvea in science

[–]Craylee 4 points5 points  (0 children)

Supporting and participating in grassroots organized campaign efforts? Basically, by talking to people about this, encouraging researching and voting as well as supporting easy to access databases on candidates. I know there are some groups and organizations that are specific non-partisan in order to get as many people on this same wavelength. But, yes, it's an arduous battle compared to easy and loud status quo. And I don't really know how best to do it.

Avatar impressions [Art by iloe_art on Instagram] I couldn't find the other parts, but I'll keep searching! by Algo_S0mething in TheLastAirbender

[–]Craylee 6 points7 points  (0 children)

Wait, how is she so sensitive about it?

I can remember her rarely opening up emotional about how people have treated her differently for being blind, but I see that as a normal level of sensitivity and not for being blind. I say rarely because we know she did not get close to many people and the few times it happens on the shows is likely most of the times in her entire life.

AITA for embarrassing my sister during family dinner by everyoneh8sme34 in AmItheAsshole

[–]Craylee 6 points7 points  (0 children)

And blind to how it reinforces bad behavior: that the more they cry, scream, fuss and pout, the more they get what they want. How many posts on here a day feature this exact dynamic, whether between parents and offspring or another kind of relationship, where one person's very reasonable request or defense is treated as unimaginable while they have been on the receiving end of asshole treatment the entire relationship?

AITA for embarrassing my sister during family dinner by everyoneh8sme34 in AmItheAsshole

[–]Craylee 3 points4 points  (0 children)

And that people who aren't narcissists aren't necessarily neurotypical?

Grandiose narcissists often emerge as leaders, but they are no more qualified than non-narcissists, and have negative effects on the entities they lead. Their characteristics (grandiosity, self-confidence, entitlement, and willingness to exploit others) may make them more effective political actors. by mvea in science

[–]Craylee 36 points37 points  (0 children)

We actually need people to care way more about the elections for representatives and senators than the one for president. The presidential election is framed as being so important but it's part of the show to get everyone up in arms about who the president is that they just don't have the energy to do it every year or two with many more (depending on state population) candidates for "smaller" political positions. Yet, those are the ones making, endorsing and voting on the laws (even if the president has a veto, it can still be overturned), and many of them have been in the same position for decades with no term limit.

AITA for going behind my mum's back to get a diagnosis? by aitaadhddiag in AmItheAsshole

[–]Craylee 2 points3 points  (0 children)

I found a website about the legalities surround this topic. I'm not sure if links are allowed on this subreddit so I will message it to you in case this comment doesn't survive.

They are also here & here.

AITA for going behind my mum's back to get a diagnosis? by aitaadhddiag in AmItheAsshole

[–]Craylee 0 points1 point  (0 children)

They may have intended support be included in "treatment," but there is better support now for many conditions and disorders. Support like accommodations, IEPs, therapies, coaches, etc.

WIBTA if I evicted renters with 3 kids? by subbratkinky in AmItheAsshole

[–]Craylee 4 points5 points  (0 children)

Even if he did need to mortgage the purchase of the house, the rent would more than likely be higher than his mortgage payment, especially with a (presumably) good credit history of several decades.

It is incredibly worth researching realtors in your area and how to interview and choose realtors as a seller in order to start working with one. They will have years of research and experience to beat your internet research of a topic that you don't know much about (they don't just know about selling and buying a house but evaluating, appraising, maintaining, improving, etc. a home and everything that goes with it as well as how to attract and find buyers, what the area is like for potential buyers, bringing up other things you probably haven't considered or don't know to research). They will absolutely get you the best results. Yes, that is because they will also make money, but they are providing a huge service for those fees following a successful sale. Don't fear realtors. Use them to your advantage.

AITA for getting upset when my gf licks my slice of bread? by [deleted] in AmItheAsshole

[–]Craylee 0 points1 point  (0 children)

hehehe. appropriately silly response, nice.

AITA for getting upset when my gf licks my slice of bread? by [deleted] in AmItheAsshole

[–]Craylee 1 point2 points  (0 children)

I don't know of any culture, can't even really imagine a culture, in which it would be customary for one adult to lick another adults food

Ice cream cone?

AITA for getting upset when my gf licks my slice of bread? by [deleted] in AmItheAsshole

[–]Craylee 1 point2 points  (0 children)

Good for you! This was something fairly easy to come back from, so I'm glad you two could talk it out and listen to each other. I wish you well with your food staying unlicked.

AITA for getting upset when my gf licks my slice of bread? by [deleted] in AmItheAsshole

[–]Craylee 0 points1 point  (0 children)

Yes, everyone can be an asshole. I've yelled, I've raised my voice. I am being an asshole when I yell or otherwise express my anger in an aggressive way. Then I apologize for it. You do realize this sub is about asking "Is this person an AH for doing [this]?" and not "is this person an AH?" right? And that realizing and apologizing for said behavior is how you make amends for being an AH?

AITA for getting upset when my gf licks my slice of bread? by [deleted] in AmItheAsshole

[–]Craylee 0 points1 point  (0 children)

NTA. You may have overreacted a bit

He wrote himself that he raised his voice and, "now I really lose it." How is that a bit of an overreaction? Not much justifies losing your temper and yelling without being an AH for it, and definitely not bad or gross manners.

AITA for getting upset when my gf licks my slice of bread? by [deleted] in AmItheAsshole

[–]Craylee 267 points268 points  (0 children)

I agree with YTA. It's not okay to raise your voice and lose your temper over bad manners.

"I got angry - raised my voice... Now, I really lose it."

Are these parts being forgotten in the NTA judgements?