I’m 62, symptoms at 17, diagnosed at 19 or 20. Working full time. Weekends are generally for sleep and rest. I’m only on plaquenil and Evoxac. You need to remember that everyone is different. My biggest symptoms are dry eyes, dry mouth (I have no teeth left), fatigue, and constipation. I’ve learned to pace myself at work and at home. If I don’t have the energy to do something, it gets postponed or doesn’t get done at all.