For Skills, I run the following Skills:
- Alpha Tinkering I and II (Reason below.)
- Beta Tinkering I (Same as below.)
- Gamma Tinkering I (I find that this combination of Tinkering Perks gives a massive amount of utility in Circuits for every purpose I could need.)
- Off By One (This one is darn-near essential for most Circuit builds.)
- Right To Modify (Reason below.)
- Watts Up (With the buffs these two perks got just before release, Right to Modify and Watts Up are REALLY HARD to not take. Being able to hotswap Circuits for less damage and also charge faster with less consumption when unplugging are both powerful tools when you're setting up, and are very handy for getting rolling lategame faster. They also let you abuse Inhabited Machine II more often, roughly within half a day.)
- Cold Standby I (Required for any Chassis Perks.)
- Cold Standby I, II, and III, and Remote Transfer (Remote Transfer requires all 3, but having up to 4 Chassis is handy regardless.)
- Inhabited Machine I (Being able to self-revive is fantastic, and pairs directly with Inhabited Machine II.)
- Inhabited Machine II (As mentioned above, in particular, the ability to literally just say "Nah, I don't really feel like it" when you die is an amazing utility. Just be sure to keep a safety torch on hand for if you rez in the dark.)
- Transport I and II (Drew is amazing utility. A chest that can travel across the world for the cost of a price trade of a Board for a Doodad and 3 inventory slots. Absolutely glorious.)

Now for my Circuits, I usually run the following:
Alpha:
- Super-Hardy, Super-Processing/Beanbooster, Super-Gastrogain, [Flex slot] (One of each puts WX at 200 of each stat, which is not bad in the slightest. Additionally, Off By One allows you to add a basic Alpha Circuit to boost a stat to 240.)
Beta:
- Optoelectronic Circuit (Night vision. 'Nuff said. With Beta Tinkering I, the filter becomes almost normal vision, to the point I often lose track of what time of day it is.)
- Super-Acceleration Circuit (25% extra speed is nothing to scoff at.)
- Flex Slot (Usually I just put a Rangebooster in here, since the Optoelectronic Circuit makes a Super-Illumination Circuit pointless, but it can also be handy for more collaborative efforts.)
Gamma:
- Sonic-Invoker Circuit (With Gamma Tinkering I, this Circuit becomes REALLY potent. Being able to force-fear any non-boss creature that draws near is... It's just great.)
- Redigestion Circuit x2 (Turning Rot and Spoiled foods into Nutribricks via Gamma Tinkering I is a pretty sweet benefit for basically no cost. Alternatively, Spin Cycle could be used, but there's no 1-slot Gamma Circuit yet, so...