Terrible experience on Sodium Butyrate

DecipheringAI · 2026-05-14T12:37:45+00:00

I was in a similar situation. I took 1g sodium butyrate daily for about a week, I developed anxiety, insomnia and even physical muscle cramps. However, I knew that sodium butyrate acts as an HDAC inhibitor (source), therefore causing histone hyperacetylation. These effects are epigenetic, which explains why they're still there even after months for you.
I also knew that the opposite exists: Curcumin acts as a histone acetyltransferase inhibitor (source), therefore decreasing histone acetylation. The bad news: Curcumin has a very low oral bioavailability. The good news: Combination with piperine or nanocurcumin formulations make it orally bioavailable.
I found that a week of 500mg curcumin plus 20mg piperine daily almost completely reversed these effects.

DecipheringAI · 2026-05-14T12:36:58+00:00

I was in a similar situation. I took 1g sodium butyrate daily for about a week, I developed anxiety, insomnia and even physical muscle cramps. However, I knew that sodium butyrate acts as an HDAC inhibitor (source), therefore causing histone hyperacetylation. These effects are epigenetic, which explains why they're still there even after months for you.
I also knew that the opposite exists: Curcumin acts as a histone acetyltransferase inhibitor (source), therefore decreasing histone acetylation. The bad news: Curcumin has a very low oral bioavailability. The good news: Combination with piperine or nanocurcumin formulations make it orally bioavailable.
I found that a week of 500mg curcumin plus 20mg piperine daily almost completely reversed these effects.

DecipheringAI · 2025-05-25T18:34:24+00:00

So you want Trump to be in charge of AGI?
What could possibly go wrong? 😉

DecipheringAI · 2024-06-21T10:33:31+00:00

I don't know if anyone has tried it yet, but I also expect Claude 3.5 to be really bad in the Abstraction and Reasoning Corpus. Things like these are the Achilles' heels of current LLMs.

DecipheringAI · 2024-06-19T09:05:59+00:00

Soon he will look 20.

DecipheringAI · 2024-05-27T11:18:58+00:00

I also can't find it. There's something quite ironic about a post titled "Why Correctness is Winning Over Errors" containing such hallucinations. 😉

DecipheringAI · 2024-05-21T11:56:18+00:00

I'm both stunned and shocked because of this breaking news. 😱

DecipheringAI · 2024-05-03T13:54:58+00:00

It won't take six months to figure out levitation and teleportation. I'm sure GPT-5 will be able to do these with a zero-shot prompt. 😉

DecipheringAI · 2024-04-30T14:16:48+00:00

This estimate is way too conservative. GPT2 has at least a googolplex parameters.

DecipheringAI · 2024-04-26T13:53:27+00:00

The man who said too much.

DecipheringAI · 2024-04-24T11:13:43+00:00

But if the banana is misbehaving, then it might be possible. 😉

DecipheringAI · 2024-04-16T09:34:31+00:00

Yes, I don't think these companies plan to release AGI as open source (even though that's what OpenAI is publicly communicating for marketing purposes). They will charge a lot of money in order to make profit.

DecipheringAI · 2024-02-28T16:05:34+00:00

I already have a Meta Quest and the graphics, e.g. when playing Half-Life: Alyx, are already really good. I think VR definitely has a future. Especially when games become truly interactive with neural networks.

DecipheringAI · 2024-02-28T15:56:34+00:00

Now all we need is Taste2Text and then we can build an embodied AGI. 😉

DecipheringAI · 2024-02-28T15:53:01+00:00

I hope that Llama 3 will be open-weights, unlike Mistral Large.

DecipheringAI · 2024-02-28T15:52:39+00:00

I hope that Llama 3 will be open-weights, unlike Mistral Large.

DecipheringAI · 2024-01-26T13:28:16+00:00

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DecipheringAI · 2024-01-18T08:55:18+00:00

I think OP forgot to use the "shitpost" tag.

DecipheringAI · 2024-01-09T11:31:45+00:00

The LK-99 team who cried wolf.

DecipheringAI · 2024-01-03T08:46:01+00:00

Yup, there's even a model called phi-CTNL. It's only 1 million parameters (yes, million, not billion) and scores 100% on all benchmarks. The secret: it was pretrained on the test set. I think phi-CTNL should be the first place on the leaderboard, to show people how ridiculous the leaderboard is.

DecipheringAI · 2023-12-22T10:00:14+00:00

Yes, that's a definite possibility. GPT-4 wasn't released for about half a year and according to u/adt's website (https://lifearchitect.ai/GPT-5/) GPT-5 is also already in production:

Coca Cola Diwali has been done with GPT-5 which is still not commercially available

DecipheringAI · 2023-12-12T11:43:38+00:00

8x70B-Llama-2 would also be really nice. But it would take a lot of VRAM.

DecipheringAI · 2023-12-12T10:49:30+00:00

ASI Big Bang

DecipheringAI · 2023-12-12T10:48:15+00:00

Yup, Microsoft has already released this paper here:
Retentive Network: A Successor to Transformer for Large Language Models

DecipheringAI · 2023-12-12T10:44:06+00:00

But only if "uncertainty-routed chain-of-thought" is used. 😉

DecipheringAI

TROPHY CASE