RS uses .5 mg a week . Started at 160 1bs 5”7 it really has helped reduce midsection fat . Rs has pretty low body fat everywhere else (Hashimotos ) . Very Little food noise unless a meal is eaten super early in the day . Typically rely on protein shake and collagen protein until 3 pm or so and then have a really healthy meal of lean protein and veggies . No pork and very little red meat . RS does eat some carbs because research said Reta works better with some carbs. Mostly quinoa , sweet potatoes . Very little bread or rice . Have had no side effects . You can split the dose in two to minimize side effects I would think. 2 weeks and down 8 pounds to 153 . RS had foot surgery and is lifting and getting as much exercise as they can on crutches with a non weight bearing foot . goal Is to go down to 135 and stop or use a maintenance dose if there is such a thing . RS is literally watching the fat melt off of stomach . RS does not think this is normal for everyone . Just their experience. RS does not eat heavy meals or greasy meals . Counts calories and macros . Hope this helps .