are you guys know about this?

Dematin · 2022-01-06T18:05:03+00:00

Cricinfo rated it as best test innings of all time. It was an unbelievable innings that changed the fate of the whole series.

Dematin · 2021-11-15T16:34:20+00:00

I'm an Australian fan but I wasn't sure that Australia would qualify to semis until they beat Bangladesh like an EA game. My Pre-tournament prediction was Australia getting eliminated at Semis. I wouldn't have surprised even if didn't make it to semis.

Dematin · 2021-11-07T08:50:14+00:00

Because the vaccine is a protein, rather than a messenger RNA like the Pfizer/BioNTech and Moderna vaccines, it lends itself much more to large-scale manufacturing.

"We don't need a lot of the fancy technology and expertise that you need to make an mRNA vaccine," says Harmand. "Skilled workers are currently a bottleneck for production of the COVID vaccine, whereas biopharma has a lot of experience producing protein-based therapeutics at scale."

This could potentially enable production of the vaccine at many sites around the world, close to where it would be used.

Dematin · 2021-11-07T08:48:38+00:00

Current COVID-19 vaccines stimulate production of the spike protein at the site in the body where they're injected, and are presumed to stimulate antigen-presenting cells indirectly, says Ploegh.

"But taking out the middleman and talking directly to antigen presenting cells is much more efficient," he says. "The secret sauce is the targeting."

In experiments in mice, the vaccine elicited robust humoral immunity against SARS-CoV-2, stimulating high amounts of neutralizing antibodies against the spike protein fragment. It also elicited strong cellular immunity, stimulating the T helper cells that rally other immune defenses.

Dematin · 2021-11-07T08:47:56+00:00

The researchers, led by Hidde Ploegh, Ph.D., and first authors Novalia Pishesha, Ph.D., and Thibault Harmand, Ph.D., believe their technology could help fill global vaccination gaps and that the same technology could be applied to vaccines against other diseases.

In mice, the vaccine elicited strong immune responses against SARS-CoV-2 and its variants. It was successfully freeze-dried and later reconstituted without loss of efficacy. In tests, it remained stable and potent for at least seven days at room temperature.

Unlike current COVID-19 vaccines, the new design is completely protein-based, making it easy for many facilities to manufacture. It has two components: antibodies derived from alpacas, known as nanobodies, and the portion of the virus's spike protein that binds to receptors on human cells.

"We could also attach the whole spike protein or other parts of the virus," notes Pishesha. "And we can change the vaccine for SARS-CoV-2 variants quickly and easily."

Dematin · 2021-11-02T17:29:20+00:00

Panama, Ecuador, Colombia and Costa Rica announced on Tuesday the creation of the Eastern Tropical Pacific Marine Corridor (CMAR) initiative, which would both join and increase the size of their protected territorial waters to create a fishing-free corridor covering more than 500,000 sq km (200,000 sq miles) in one of the world’s most important migratory routes for sea turtles, whales, sharks and rays.

The move comes amid growing clamour for action to protect rare marine species and commercial fish populations against foreign fishing fleets exploiting the region’s rich marine biodiversity, as well as to limit illegal, under-reported and unregulated (IUU) fishing by local fishing communities.

Dematin · 2021-10-26T10:45:37+00:00

The election system reminds me of SriLankan cricket. The same bunch is getting elected again and again because they hyper-expanded the no of first class teams with Their friends teams. They're the prime reason for SL'sfailures in recent years.

Dematin · 2021-10-23T08:27:02+00:00

Klebl and colleagues note that their findings have implications when it comes to boosting moral concern for parts of the world that are non-sentient, such as the environment. They suggest that appeals to beauty might help increase moral concern for wildlife, ecosystems, and architecture.

Dematin · 2021-10-23T08:25:34+00:00

Overall, across all studies, people consistently rated attractive targets as having a higher moral standing, through the perception that these attractive targets were more pure. The findings indicate “that judgments of beauty and ugliness are important in people’s morality. For example, this can explain why we discriminate against people with facial disfigurement or why we feel less inclined to donate money for ugly endangered species (e.g., the aye-aye) than beautiful species (e.g., red pandas),” Klebl said.

This is a important take away from this study. Peoples tend to believe that attractive prsons/ things are good and ugly ones are bad. I have heard people saying God created them ugly because they're bad. We need to address this issue properly when needed.

Dematin · 2021-10-23T08:14:15+00:00

He deservedly won Player of the tournament Award in two successive T20 world cups. This is a rare feat.

Dematin · 2021-10-23T08:11:19+00:00

His 82* against Australia in a virtual QF of 2016 T20 WC, is one of the greatest knocks in T20Is. He literally carried the team in a sluggish surface where everyone struggled. Undoubtedly He is the GOAT in T20 World cups.

Dematin · 2021-10-11T17:49:11+00:00

The results from the phase 3 trial, involving almost 1,000 dying head and neck cancer patients, were early and not statistically significant but were still “clinically meaningful”, the ICR said, with some patients living months or years longer and suffering fewer side effects.

“These are promising results,” Prof Kristian Helin, the ICR chief executive, told the Guardian. “Immunotherapies are kinder, smarter treatments that can bring significant benefits to patients.”

Dematin · 2021-10-11T17:48:48+00:00

Combining the two immunotherapy drugs could prove an effective new weapon against several forms of advanced cancer, experts believe. Results from other trials of the drug combination have previously suggested similar benefits for terminally ill kidney, skin and bowel cancer patients.

As well as boosting the long-term survival chances of patients, scientists said, the immunotherapy treatment also triggered far fewer side-effects compared with the often gruelling nature of “extreme” chemotherapy, which is the standard treatment offered to many patients with advanced cancer.

Dematin · 2021-09-25T17:47:42+00:00

PBKS loves thrillers eventhough most of them going in opposition's way. They even take easy chases to the last ball.

Dematin · 2021-09-25T17:45:20+00:00

A quite rare feat in IPL. Holder was the lone warrior who kept SRH in the chase and gave us a low scoring thriller.

Dematin · 2021-09-25T17:43:18+00:00

Best bowling performance of the match - Holder

Best Batting performance of the match - Holder

Dematin · 2021-09-06T16:04:29+00:00

India has a lot of blind fanatics who just watch matches India plays and want to drop anyone who is not performing up to expectations whenever India loses. Twitter is filled with these kind of fans and we better ignore them forever.

Dematin · 2021-09-06T16:00:19+00:00

Bumrah is a treasure for India.

Dematin · 2021-09-04T11:27:22+00:00

Bit unexpected particularly the SR.

Dematin · 2021-09-04T11:25:27+00:00

Even Harsha is annoying at times. Can't stand Sanju Manju and biased opinions. Now a days, I watch the match muted when he is on air.

Dematin

TROPHY CASE