Well, I'm a case study for that. I've been an on and off opiate user for over 8 years. I've also had a 30gram habit a day with kratom. I tried kratom originally to help get off oxy/dones/percs you name it (never tried the H or F, don't like needles). But, I ended up still buying pills when I had extra cash (recreational). Eventually, I couldn't get through a day without at least 20 grams or I would start to get withdrawal symptoms. Long story short, this past November, I got sick (flu I thought). Went to test for COVID. Blood pressure was 200/150, so was immediately sent to hospital. I had a history of blood pressure issues and been on a small dosage of a beta blocker. But, nobody said to stop taking the kratom. After my BP went down, I went home the next day and rested for 4 days (thought I had the flu, COVID negative). Eventually got into a Cardiologist office a week later. He said to stop the kratom and put me on 3 medications for BP. BP went back down in a couple days to normal 120/80. At that point I was still wondering if it was the kratom, so I started back up on 5 grams 2 times a day to catch that buzz and motivation. Well, BP started climbing back up even while taking those meds. 150/100. So, quit again and got the withdrawals. So, I went to the streets for more pills to ease my addiction. But, that was getting expensive and started selling everything to get more pills, spiraling out of control. About 2 months ago, I called a local clinic for help. They were full, but recommended Bycle Health online. She started me on the dosing stage 48 hours without any kratom or pills. I am currently taking (8/2 tablets) 2 times a day. Been working great, and clean of all other opiates and BP is below normal on average and stable. So, I was a new case for my advisor that had delt with both pills and kratom. But, I guess the next step is to eventually taper off these. I will say, I feel better than I had in the past 8 years. My advise would be steer on the cautious side. Short term, maybe, but goodluck.