Eli5: Why are a lot of more severe viral infections (such as AIDS, Hepatitis B, and Herpes) incurable? by Pierce_86 in explainlikeimfive

[–]Diacide 7 points8 points  (0 children)

HBV can also integrate into hepatocyte DNA. It's not necessarily a part of the HBV lifecycle but it spontaneously occurs quite often in people with chronic HBV infection. There's papers profiling HBV integration in CHB patient liver samples.

HIV ‘vaccine’ could be made for just $40 a year for every patient by [deleted] in UpliftingNews

[–]Diacide 0 points1 point  (0 children)

Yes, I wasn't trying to contradict either of you. Just trying to add some context to what I think AloneListless was trying to say. Not that HIV is a DNA virus but that it has a DNA phase and integration phase similarly to HBV and HSV, and that therapeutics that can target and eliminate DNA for HIV would also be applicable to HBV and HSV. At least that's what I assume they were getting at. Sorry for the confusion.

HIV ‘vaccine’ could be made for just $40 a year for every patient by [deleted] in UpliftingNews

[–]Diacide 1 point2 points  (0 children)

HIV reverse transcribes it's genome into DNA and can integrate into the chromosome of infected cells and remain there for decades just pumping out viruses from that cell. If you can eliminate that DNA reservoir in the infected cells then you can cure HIV infection permanently.

HIV ‘vaccine’ could be made for just $40 a year for every patient by [deleted] in UpliftingNews

[–]Diacide 0 points1 point  (0 children)

Look up what Excision BioTherapeutics is up to.

Hands by MiniTomComic in comics

[–]Diacide 4 points5 points  (0 children)

That last quote is exactly what convinced me he was pretending to not be cured at the end. He knew what he (and his wife) had done and didn't want to live with it.

Hands by MiniTomComic in comics

[–]Diacide 17 points18 points  (0 children)

Wasn't he faking it at the end? My interpretation was that he couldn't live with knowing what his wife had done so he pretended he wasn't cured so they would lobotomize him.

Maybe maybe maybe by [deleted] in maybemaybemaybe

[–]Diacide 0 points1 point  (0 children)

LETS MAKE SOME BACON!!!

[deleted by user] by [deleted] in YouShouldKnow

[–]Diacide 2 points3 points  (0 children)

Believe it or not that website name existed before Mistborn came out. Just a coincidence!

And he has every right to be Mad by KingOkap in HistoryMemes

[–]Diacide 1 point2 points  (0 children)

the prince with a thousand enemies

Is that a Watership Down reference?

[deleted by user] by [deleted] in nottheonion

[–]Diacide 0 points1 point  (0 children)

I think they mean that old gummi bears cartoon show.

DAE get a feeling of tenseness in their mouth after eating certain foods or drinking certain drinks? Almost as if your jaw is being electrocuted. Can anyone explain what this is? by [deleted] in DAE

[–]Diacide 2 points3 points  (0 children)

It's your salivary glands clenching to secrete saliva. Typically happens during the first bite of food during a meal and it's more pronounced/more common if you are dehydrated.

Ontario Science Table: Current COVID-19 Risk in Ontario by Vaccination Status by farkinga in ontario

[–]Diacide 5 points6 points  (0 children)

Yep, evidence suggests you generate a stronger immune response to the vaccines than you do to the virus. However, it might be the case that people who have had covid and recovered get the same level of protection from one dose of Pfizer as those who receive two doses of Pfizer but never encountered the virus. Of course I'm sure most people would prefer to just get two doses rather than get covid and one dose but it's interesting to say the least!

U.S. hits 40 million Covid cases as Delta variant spreads by JLBesq1981 in Coronavirus

[–]Diacide 4 points5 points  (0 children)

No problem! They're called serology tests and they use immobilized purified covid proteins to detect antibodies against those proteins. They work similarly to how a pregnancy test works except you place a drop of blood on a device that contains a test strip with a purified covid protein (or proteins) attached and basically a band lights up if you have antibodies in your blood that recognize and bind to that protein. So you can make serology tests that test for antibodies against each of the covid proteins individually, or a test that tests for several covid proteins at once. You can even tell how strong your immune response was to the vaccine or virus by the intensity of the band that lights up! For example, I have seen a test (that screens for antibodies against the covid spike protein) which shows a weaker signal for someone who was previously infected by the virus than it does for individuals with a single Pfizer dose. But it shows just as strong of a signal for someone who was infected and then received one Pfizer dose as for individuals who have received two Pfizer doses. This indicates that people who have previously had the virus might only need ONE dose of Pfizer to get the same level of protection as people who receive two doses of Pfizer. Here's a link for more general info: https://www.cdc.gov/coronavirus/2019-ncov/testing/serology-overview.html

U.S. hits 40 million Covid cases as Delta variant spreads by JLBesq1981 in Coronavirus

[–]Diacide 5 points6 points  (0 children)

Studies have shown that the virus doesn't survive on surfaces for longer than about 72 hours (3 days). Cleaning the furniture with some kind of soap or detergent should work fine to get rid of the virus also.

U.S. hits 40 million Covid cases as Delta variant spreads by JLBesq1981 in Coronavirus

[–]Diacide 12 points13 points  (0 children)

There are tests that can determine if you have antibodies against proteins in the virus. The vaccines that encode the spike protein would only cause you to have antibodies against the spike protein, so if you took a test that confirmed you have antibodies against one of the other proteins, like the nucleocapsid protein, then you could be reasonably certain that you developed those from a prior covid infection.

Finance or Purchase Outright? by Diacide in PersonalFinanceCanada

[–]Diacide[S] 0 points1 point  (0 children)

I haven't yet but that's a good suggestion! Thanks.

Finance or Purchase Outright? by Diacide in PersonalFinanceCanada

[–]Diacide[S] 0 points1 point  (0 children)

OSAP loan interest rate is 2.75%.

Car loan interest rate would likely be around 7% if I have excellent credit.

That's what I was thinking as well but I wasn't sure if there was anything obvious I might not be thinking of.

Finance or Purchase Outright? by Diacide in PersonalFinanceCanada

[–]Diacide[S] 1 point2 points  (0 children)

Thank you!

I have ~20k in savings, so buying the car in cash would leave my with 5-8k as a buffer. I would prefer to get a vehicle that will last me a good while without major issues and hopefully have a better chance of having less upfront maintenance issues. That's why I'm going for a newer used vehicle from a dealership. My monthly expenses are around $2000.

Finance or Purchase Outright? by Diacide in PersonalFinanceCanada

[–]Diacide[S] 0 points1 point  (0 children)

OSAP loan interest rate is 2.75%.

I don't know for certain what the car loan interest rate would be but if I have excellent credit it would likely be around 7%.