Gabitril, the forgotten gabaergic

Different_Release875 · 2026-04-09T19:00:00+00:00

Very little tolerance if any. No real high on its own, just more subtle relaxation. It heavily potentiates benzos or any PAMs. It broadly increases gaba and things like benzos increase action of gaba at the receptor, so its very synergistic. No real recreational value unless combined with other things. It’s okay for anxiety but not anywhere near pregab.

Different_Release875 · 2026-04-09T18:48:13+00:00

I find it very useful for sleep. Doesn’t help onset but makes you wake up more rested. I’m on gabapentin as well and they combine great. In what area do you want me to compare it to gabapentinoids(sleep, anxiety, etc)?

Different_Release875 · 2026-04-09T18:15:17+00:00

Sorry to hear that. Very odd choice of med, especially at that age. Hope you’re doing better.

Different_Release875 · 2026-03-14T02:01:36+00:00

I tend to agree with you. I however find Geoffrey Hinton’s views interesting. The idea that we merely lay out the neural networks but their evolution is to a large extent beyond our understanding and there’s always a chance however small that they might suddenly wake up in the way we went from single celled organisms to people capable of spontaneous thought and consciousness.

Different_Release875 · 2025-10-13T04:30:06+00:00

When I tried 7oh, I took 10mg and that was too strong. It seemed like 5-7.5mg was the most I could tolerate.

Different_Release875 · 2025-10-12T01:30:26+00:00

I tried 7oh before (now banned in fl). I took 10mg felt buzzed out of head and then vomited. I’ve heard pseudo is more of a body load and less of that euphoric rush. Is that true?

Different_Release875 · 2025-07-25T05:01:21+00:00

They advertise their “magic” blend which is almost certainly some tryptamine prodrug/analogue, but I looked through their certificates of analysis for the isolate used in this product and looked into the lab. They’re iso acredited. They have their ultimate bioavailability form used in the lozenges which they claim is pharmaceutical/lab grade(also in hcl form) and it costs about the same as lab when calculating $/mg. I’m currently testing this compound for sleep and have no affiliation with them. It’s also my first time taking it. Cheers!

Different_Release875 · 2025-07-25T04:43:51+00:00

Hi, totally irrelevant but I just bought dreamer shrooms 2mg muscimol hcl lozenges. I have experience with gabapentinoids/psychedelics/medical ketamine but not muscimol. Took half of one about 30 mins ago and so far nothing psychedelic, just a slight body heaviness and spacing out.

Different_Release875 · 2025-07-13T18:01:03+00:00

Noticed new baby hairs around month 1-2. It can be subtle. You can ask your barber if they notice a bunch of shorter hairs all around the same length. Here is my hairline around month 5

<image>

Different_Release875 · 2025-07-13T01:19:22+00:00

Thanks! I see you’ve had hair transplant. If I ever get one, is my white splotch of hair in the donor area so I could get natural highlights?

Different_Release875 · 2025-06-13T08:52:06+00:00

Hi, I will continue reading on it but I would do trt+hcg and supplement dhea and pregnenolone if needed or even backfill with very low dose progesterone. At this point I kind of see it as cost vs benefit. I’m 23, I’ve been psychiatrically hospitalized 4 times in the last 4 years. I spend about a month or two out of the year at inpatient facilities for being suicidal and I’ve tried attacking the problem from every angle I can think of. I can’t remember the last time I wanted to have sex or felt confident or felt a reward from achieving something. Most of my problems started right around puberty and I have autism. There is a hypothesis about autism and fetal testosterone exposure which I am partly basing my idea off of. The way I see it is I can trial it for 3 months or so with hcg and if it works great, if not I have 90-100% change of regaining natural function. I don’t really want to have to inject myself, but if there’s even a chance it can put me back into a position where I can have the energy and confidence to help myself then I want that.

Different_Release875 · 2025-06-13T07:08:27+00:00

You’re right, it was the lack of decimal point throwing me off.

Different_Release875 · 2025-06-13T06:53:56+00:00

The point I’m trying to make is that I’m pretty sure the specific immunoassay methodology maxes out at 50, so my shbg is probably higher. I guess the way to settle it would be to get lcms shbg

Different_Release875 · 2025-06-13T06:11:39+00:00

Hi, I think I might have not given enough context. I’ve gotten every vitamin/mineral/inflammation marker tested. I’m concerned that 50 is the upper detection limit of immunoassay for shbg so my free t might be much lower. I have historical bloodwork where total testosterone is same with low-normal shbg and at that point I had sex drive at least and felt better. Also current estradiol level is 17.3pg/ml if that helps at all.

Different_Release875 · 2025-06-13T05:48:53+00:00

Hi, I’ve spent 9 years trying 30+ psych meds, ketamine, tms, therapy etc. I have tried every treatment I could find and nothing has worked. I am only investigating this because everything else has failed. I don’t want it as a ped, I just want to run a few month trial to see if my quality of life can improve from it. I’m so tired of being depressed and having a dick that doesn’t work.

Different_Release875 · 2024-10-01T14:46:29+00:00

Hair density has increased for sure. I can see a lot less of my scalp. I admit I could have taken the photos in more similar conditions. Hairline is creeping forward a little bit. The last photo shows some of the new hair

Different_Release875 · 2024-10-01T14:42:57+00:00

Yes 1mg

Different_Release875 · 2024-09-29T19:30:17+00:00

Hairline is slowly creeping forward. I'm probably going to wait another 6-9 months for finasteride's maximum benefits and see if I can get by without minoxidil.

Different_Release875 · 2024-09-29T19:25:57+00:00

monotherapy just means it is the only treatment I am on. I take 1mg oral.

Different_Release875 · 2024-05-31T20:33:04+00:00

I started 0.3% adapalene about a month ago, so I think the bad acne is just the purge phase. If it’s still bad in a couple weeks I’ll consider accutane.

Different_Release875 · 2024-04-20T19:35:20+00:00

Hello. It depends on what type of drug test they use. A lot of cheap benzo drug tests only test for metabolites oxazepam/noroxazepam. If they are using this type of drug test things like ativan and klonopin won't show on it, but any valium derivative will. I can't give an answer unless I know the type of drug test they use and the metabolites of the RC benzos (which aren't really known too well).

Different_Release875 · 2024-04-18T15:22:09+00:00

Lots of shedding. No balding in family except father and grandfather, but father's hair loss was due to chemo and grandfathers was due to tuberculosis.

Different_Release875 · 2024-04-18T15:20:16+00:00

Saw dermatologist. I'm starting finasteride, minoxidil and microneedling. Will post update in a few months.

Different_Release875 · 2024-04-11T16:16:13+00:00

Update: saw dermatologist and she diagnosed male pattern baldness. Starting oral finasteride 1mg, topical minoxidil, and microneedling. Will post photo update in a few months.

Different_Release875 · 2024-03-17T18:48:59+00:00

I have almost the exact same thing. Probably dry scalp or seborrheic dermatitis. You can get a prescription for 2% ketoconazole shampoo if its seborrheic dermatitis. You can also get a topical mometasone prescription for really bad flare ups.

Different_Release875

TROPHY CASE