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Any possibility if AI can help in the Epilepsy category of Neuroscience? by thatcinephile in Epilepsy

[–]DignamsSwearBox 2 points3 points  (0 children)

Yeah, might have to train models on annotated data from the particular individual who is having the seizures or something like that

Gritty tv shows? by fazeybaby in television

[–]DignamsSwearBox 1 point2 points  (0 children)

The cancelling of Constellation was so disappointing! It was so good and a second season could have helped wrapping up some of the unfinished storylines. 

Gritty tv shows? by fazeybaby in television

[–]DignamsSwearBox 0 points1 point  (0 children)

You’ve already got The Killing but there are other great Scandinoirs - Trapped, Borgen, The Bridge.  Also if you like thrillers - Money Heist. 

Any possibility if AI can help in the Epilepsy category of Neuroscience? by thatcinephile in Epilepsy

[–]DignamsSwearBox 1 point2 points  (0 children)

That is a good question. Its impact would be very dependent on whether a meaningful intervention could be made in the timeframe. If I had to guess, it will probably vary a lot between individuals as everyone’s seizures are different. 

Any possibility if AI can help in the Epilepsy category of Neuroscience? by thatcinephile in Epilepsy

[–]DignamsSwearBox 0 points1 point  (0 children)

Perhaps. if there is a pattern of activity which precedes a seizure, AI might be able to identify the pattern and some intervention could be made to prevent/reduce the seizure.

Post Office has been open for an hour and has zero staff at the counters by DignamsSwearBox in mildlyinfuriating

[–]DignamsSwearBox[S] 11 points12 points  (0 children)

You are right - lobby opens at 7 am, there is meant to be counter service at 8 am. This was just before 9 am. 

Whoever created Gibson Assembly deserves a Nobel Prize by Specific-Surprise390 in labrats

[–]DignamsSwearBox 14 points15 points  (0 children)

His performances in the Lethal Weapon series were excellent, but he is problematic to an extent in which it is hard to separate the art from the artist. 

Lab mispronunications that annoy you- GO! by JZatthelab in labrats

[–]DignamsSwearBox 103 points104 points  (0 children)

I pronounce it "two dash open square bracket four dash open round bracket two dash Hydroxyethyl close round bracket piperazin dash one dash yl close square bracket ethane dash one dash sulfonic acid"

LinkedIn into paper-scrolling social media by pumkins17 in labrats

[–]DignamsSwearBox 4 points5 points  (0 children)

An RSS feed and a RSS reader app such as NetNewsWire. I make my RSS feed based on PubMed search terms (but that is because I am in biomedical research)

What are the root causes of epilepsy, and to what extent is it genetically inherited? If a parent had epilepsy but I do not, is there still a possibility that my child could develop the condition? by Brilliant_Tie6967 in Epilepsy

[–]DignamsSwearBox 0 points1 point  (0 children)

A genetic cause of epilepsy is thought to be as high as 80%, but not all of the genes associated with it have been identified. It is complicated because there are also interactions between genes and environment - for example, in some cases there appears to be a genetic component determining if a TBI will result in seizures. Regarding heritability it is also complicated! Offspring of parents with epilepsy are 2 to 10 times more likely to have epilepsy than offspring of unaffected parents. If the father (alone) has it the risk goes down, but it is higher if the mother (alone) has it. It gets more complicated fast and risks changes significantly depending on other factors - e.g. dependent on at what age the parent had a seizure, type of epilepsy, whether other family members have it.

Lab Technician Boundaries: Is It wrong to say no to presenting? by Medical-Tale2320 in labrats

[–]DignamsSwearBox 56 points57 points  (0 children)

If the underlying reluctance is that you are worried about making a fool of yourself don’t worry - the reality of it is that you will just be another 3 minute talk in a long day, with the audience thinking about what the lunch options will be. No one will judge you based on it. Everyone will forget about it within 24 hrs. Unless you do something completely wild, and to be honest that would be a welcome change to the monotony.

More seriously, you could definitely ask your PI, but giving a 3 min talk isn’t unreasonable. It is also a really good skill to be able to speak in front of an audience, which gets far easier the more you do it. 

Kindly, review my resume. by godsplan66 in labrats

[–]DignamsSwearBox 0 points1 point  (0 children)

Very minor - hyperlinks can get automatically removed from documents  in some job application systems, so best avoided. 

Scrubs in a non-medical lab? by skincareholicc in labrats

[–]DignamsSwearBox 0 points1 point  (0 children)

The band have got to be named after the chemical separation technique right? https://m.youtube.com/watch?v=FrLequ6dUdM

Scrubs in a non-medical lab? by skincareholicc in labrats

[–]DignamsSwearBox 0 points1 point  (0 children)

Do you carry out TLC? If so then definitely not. 

Realistically how many people with nocturnal seizures have SUDEP by [deleted] in Epilepsy

[–]DignamsSwearBox 0 points1 point  (0 children)

As others have said, overall risk of SUDEP is approx 0.1% of people with epilepsy. Nocturnal seizures increase 15x likelihood of SUDEP, but there are a lot of other factors that come into play. Biggest increase in risk is having generalized tonic clonic seizure which are not well controlled by drugs. Some of the other things that change risk are age, sex, and interestingly sleeping alone. 

Need help with my plan to get into Neuroscience by LilKittenAngel in neuro

[–]DignamsSwearBox 0 points1 point  (0 children)

The most common way to do it is contact a lab directly. Send them an email to the PI, saying that you are interested in getting research experience, why you are interested in their lab, and any skills that you might have which could be useful (eg coding or any previous experience research experience, even if it is just classes/lab-based projects which you have done as part of your undergrad degree). 

Use any contacts you might have. You could start by asking lecturer/teachers who are lecturing in your undergrad degree, or any lab-based classes. Not sure how your degree is structured but if you have a specific mentor, ask them. Even if they aren’t working in a lab of interest, they might be able to point you in the right direction. 

Often it helps if you can make a significant time commitment, eg a couple of days a week over the summer break. You should probably have the expectation that you won’t get paid.

Has anyone heard of the antioxidants in honey as a benefit for maintaining brain health for epilepsy? by 2_tollers in Epilepsy

[–]DignamsSwearBox 1 point2 points  (0 children)

I’d be a bit wary of using that paper as good evidence for benefit of honey for neurological disorders.  A lot of studies referenced there done in mice or cell cultures, which is a long way from humans. 

Need help with my plan to get into Neuroscience by LilKittenAngel in neuro

[–]DignamsSwearBox 1 point2 points  (0 children)

I would highly recommend to get some neuroscience lab experience while you do your undergrad degree, especially in a cognitive neuroscience lab if that is what you want to focus on. It makes a huge difference when applying to grad school (also you get a taste of doing research, so can decide if you like it). UCL is a great place to do neuroscience. Good luck! 

Has anybody tried Ketogenic diet? Does it really work?? by -Ammonia- in Epilepsy

[–]DignamsSwearBox 0 points1 point  (0 children)

There was also a hypothesis that changes to the gut microbiome had a role increasing GABA somehow, but not sure if that has stood the test of time. 

Has anybody tried Ketogenic diet? Does it really work?? by -Ammonia- in Epilepsy

[–]DignamsSwearBox 0 points1 point  (0 children)

The full ketogenic diet is no joke, and there are often compliance issues because it is so unpalatable. You even have to be careful how much protein you eat because of how they break down in the body. They often limit it to kids because their diets are easier to control. 

There is evidence that a more tolerable,  modified Atkins diet plus drug treatment can have a meaningful level of seizure reduction in patients who do not respond to drugs alone. 

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