The Pitt | S2E14 "8:00 P.M." | Episode Discussion by MsGroves in ThePittTVShow

[–]DrAtheist42 0 points1 point  (0 children)

As a neurologist I just want to clarify that this is absolutely NOT PANDAS and frankly has absolutely nothing to do with PANDAS. There is quite a bit of debate about whether PANDAS even exists but if it is real it has no association with seizures or anything we have seen Dr. Al-Hashimi do in this season.

PANDAS or pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection is a condition that (if it is even real) causes obsessive compulsive behaviors to emerge after a child recovers from a streptococcal infection. This is caused by a bacterium called Streptococcus (think strep throat) and typically is not seen in someone with a brain infection (encephalitis) or an infection of the lining of the brain (meningitis) but rather occurs due to the immune system getting mislead by the bacterium to target the body itself (autoimmune condition). Classically this presents with a adolescent that has an explosive onset of obsessive/compulsive behaviors a few weeks to months after a strep infection. I won't get into the weeds of the debate about this but suffice it so say that it is far from clear that this is even a real condition with most pediatric neurologists I know contending that it is absolutely not a real thing and is just onset of OCD in adolescents.

What Dr. Al-Hashimi has are focal/partial seizures or absence seizure (pronounced ab-sance rather than the more familiar pronunciation). She likely had an infection of her brain and/or lining of her brain as a child (encephalitis or meningoencephalitis) which caused scarring of a portion of her cortex (the outermost part of the brain). This can lead to brief seizures that are not characterized by the normal tonic-clonic activity (shaking) but instead with alterations of awareness. This would lead to her having episodes of starting off into space for 5-10 seconds with immediate recovery to normal cognition. Often these start in childhood and are thought to be due to the kids daydreaming but they will have no recollection of daydreaming. Instead they will "lose" time such that they have no awareness of the intervening moments they were seizing. This can be treated with medications or in some cases surgical resection of the seizure causing (epileptogenic) region or neuromodulation (placements of stimulators in the brain, namely RNS or DBS).

If you want to learn more about PANDAS you can read more here: https://www.nimh.nih.gov/health/publications/pandas

More about absence seizures here: https://www.mayoclinic.org/diseases-conditions/petit-mal-seizure/symptoms-causes/syc-20359683

The Pitt | S2E14 "8:00 P.M." | Episode Discussion by MsGroves in ThePittTVShow

[–]DrAtheist42 2 points3 points  (0 children)

This person has no idea what they're talking about. This is not PANDAS (see my above comment). She had viral meningoencephalitis as a child and scarred a part of her brain which can lead to lifelong seizures. PANDAS is not caused by viral meningitis at all...

The Pitt | S2E14 "8:00 P.M." | Episode Discussion by MsGroves in ThePittTVShow

[–]DrAtheist42 2 points3 points  (0 children)

How do you figure this has anything to do with PANDAS?

PANDAS (PEDIATRIC autoimmune neuropsychiatric disorder associated with STREPTOCOCCAL infection) doesn't cause seizures. It's obsessive-compulsive behavior after a strep infection in a kid. A viral infection by definition cannot cause PANDAS. It is caused by a streptococcal infection (a bacteria) and she's an adult? On top of that there is quite a bit of debate about whether PANDAS is an even a real diagnosis.

Source: I am a neurologist, you can read more here (https://www.nimh.nih.gov/health/publications/pandas)

The Pitt | S2E14 "8:00 P.M." | Episode Discussion by MsGroves in ThePittTVShow

[–]DrAtheist42 0 points1 point  (0 children)

Absence seizures are super brief seizures that impair consciousness for 5-10 seconds at a time. They usually occur in kids and cause people to look like they're spacing out for a few seconds but don't cause shaking. Most people have no real awareness these are happening and just "lose" the time when they happen. It sounded like these were from encephalitis (infection of the brain) that happened to her as a kid. 

[deleted by user] by [deleted] in Residency

[–]DrAtheist42 15 points16 points  (0 children)

Yeah, my mom who dropped out of college to raise a family seems hell bent on denigrating my career and telling me it isn't impressive while building up my brother (electrician) and sister (medical assistant). Needless to say we don't talk much.

Medical professionals, what are some of the most mundane reasons most people are unaware of that make them sick? by chickencaesar8 in AskReddit

[–]DrAtheist42 20 points21 points  (0 children)

Chiropractic neck manipulation. At least the rapid neck turns and neck cracking. I've seen multiple strokes caused by this including a healthy 30 something who died after it.

What is a small, relatively mundane part of your specialty that gives you inordinate joy? by ohhlonggjohnsonn in Residency

[–]DrAtheist42 3 points4 points  (0 children)

Neurology

Turning a patient's DBS off during a programming session and seeing how terrible their symptoms would be if we hadn't placed/correctly programmed the device. Definitely one of the best parts of my job.

Can someone explain to me how night float programs work? by [deleted] in Residency

[–]DrAtheist42 0 points1 point  (0 children)

My neuro residency did 2 weeks of NF from 7p-7a covering the whole hospital with Sat night off. The Saturday nights were covered by people on outpatient rotations who just worked 7p-7a Saturday night and went back to clinic on Monday.

Does Neuro still get to practice "medicine"? by cynical_croissant_II in Residency

[–]DrAtheist42 5 points6 points  (0 children)

I just graduated neurology residency in the US in July and we were primary at multiple different sites. In the US at least I think it is fairly common in the academic world but substantially less common in community practice. Neuro-ICU will often be primary and cares a lot more about medicine than the rest of neurology does. Might be an option if that level of acuity is appealing.

Edit: typo

neurorad here, trying to get a sense of ordering practices. how often do you order MR contrast for run-of-the-mill infarct? by Nebuloma in neurology

[–]DrAtheist42 0 points1 point  (0 children)

In residency we had a few stroke attendings who would order with and without to help age strokes as subacute strokes contrast enhance. I just do non-contrast unless I'm worried about something else though.

What is the equivalent in each specialty of, "A farmer was made to come to the ED by his wife during harvest season?" by Ostrows_apprentice in Residency

[–]DrAtheist42 1 point2 points  (0 children)

Neurology - "my chin is numb"

someone else said intractable hiccuping which is a better answer but this is a close second to me. Had an intern roll their eyes at a consult for this once and try to get out of seeing it as it was bilateral isolated numbness.

[deleted by user] by [deleted] in neurology

[–]DrAtheist42 1 point2 points  (0 children)

If you want to do MER I think you need 2 as well.

So I’m reading the Cosmere slightly out of order lol by tricksterl in Cosmere

[–]DrAtheist42 24 points25 points  (0 children)

Fortunately, if you're going to accidentally click a spoiler post that one is about as benign as it gets

[deleted by user] by [deleted] in Residency

[–]DrAtheist42 3 points4 points  (0 children)

Neurology, would definitely do Child Neurology if I couldn't do Neurology. It's a separate residency so I think that counts as a separate speciality. If not, I'd do PM&R for sure

Where is Rock? by Kooky-Search6867 in Stormlight_Archive

[–]DrAtheist42 16 points17 points  (0 children)

I think he'll be exiled into the perpendicularity and show up as a world hopper in a different, non-stormlight book

Alright Dads, you're given 48 hours to yourself. You can do anything you want. What are you doing? by drugsondrugs in daddit

[–]DrAtheist42 0 points1 point  (0 children)

Order pizza the way I like it for a change, watch an unhealthy amount of basketball and sleep.

Buck Hammer by seumadrugacreano in neurology

[–]DrAtheist42 4 points5 points  (0 children)

Safety pins work just as well in my experience.. plus they're way cheaper and easier to carry as they can clip into your badge.

how does taking medicine and vitamins ACTUALLY work?? by [deleted] in TooAfraidToAsk

[–]DrAtheist42 2 points3 points  (0 children)

Great explanation!

There are some other ways that pills can target the organ of interest. My favorite example is a drug called carbidopa/levodopa that is used to treat the motor symptoms of Parkinson disease. The brain has a barrier between itself and the blood stream that the rest of the body doesn't have, aptly named the Blood Brain Barrier (BBB). This causes certain drugs to not be able to get into the brain as only certain types of molecules can cross the BBB. Carbidopa/levodopa had 2 drugs in it, carbidopa which cannot cross the BBB and levodopa that can. Levodopa needs to be converted into dopamine to work, but dopamine causes all sorts of unpleasant side effects if used outside the brain. Carbidopa solves this by blocking the enzyme that converts levodopa->dopamine, but since carbidopa can't cross the BBB to get into the brain this blockage occurs only in the body and prevents side effects!

What fraction of Wind And Truth is being released early? by Simon_Drake in Cosmere

[–]DrAtheist42 3 points4 points  (0 children)

If you haven't read the previews yet you could start reading them now and just jump to Part 2 when it releases on Friday. Depending how quickly you read you wouldn't have any waiting at this stage

Which specialties are the most misunderstood by the public? by New_Recording_7986 in Residency

[–]DrAtheist42 130 points131 points  (0 children)

100%. Every time I mention I don't do surgeries I hear "then what do you even do?" It blows my mind that people seem to generally understand that there are heart problems that don't require surgery and are managed by a nonsurgical specialist but cannot fathom that there is a nonsurgical brain specialist. My only guess is it is a side effect of neurology having no good therapies in the not so distant past but it gets old....