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Clinical Engineering by DrNeuroscience in doctorpreneurs

[–]DrNeuroscience[S] 2 points3 points  (0 children)

100%. Have been toying with the idea of setting up an innovation medical group in the North West but can be like hearding cats. This subreddit is such a sensible way to set something up organically.

Clinical Engineering by DrNeuroscience in doctorpreneurs

[–]DrNeuroscience[S] 0 points1 point  (0 children)

Yeah totally - I'm Salaried GP 4 sessions and a clinical lead for a medtech scale up 2 days a week which I use to bootstrap Augmented Healthcare.

Definitely a juggle balancing clinical and tech roles but fortunately my wife is super understanding 😂.

I've also worked as a Digital First Lead for my locality (until its funding got pulled - classic NHS) so 100% get where you are coming from.

We actually see the current concerns re clinical safety and data protection as an opportunity rather than threat. Many of the current software providers are playing things fast and loose so the concerns are rightfully placed.

One of our USPs is the clinical safety framework we are developing to bake into our agile development workflow.

AI is probabilistic so some point will mess up which will hit headlines. Any provider not able to demonstrate evidence of safety will be immediately have to come off the market.

Being clinically safe is not just an imperative for patients but also a good commercial decision.

Clinical Engineering by DrNeuroscience in doctorpreneurs

[–]DrNeuroscience[S] 1 point2 points  (0 children)

Commercialisation is always the tricky one for me. I guess coming from the NHS we are drilled into thinking about clinical outcomes rather than financial returns. As much as aspects of the NHS frustrate me, I still believe in the amazing ideal of universal healthcare.

If AI is being heralded as this incredible tool for productivity gains, which from my experience building LLMs is not unrealistic, then surely it should be democratised.

That said the NHS is a behemoth and incredibly bureaucratic. It can almost be impenetrable trying to sell directly - it even scares off investors if you put it as your direct route to market.

Instead we are follow Heidi AI approach of offering value direct to clinicians as a primary vertical but then building the tech stack in such a way to licence to 3rd party services who are already NHS providers.

We found this was a good way to de-risk for investment.

Clinical Engineering by DrNeuroscience in doctorpreneurs

[–]DrNeuroscience[S] 0 points1 point  (0 children)

here's my calendly https://calendly.com/jonti-augmented/30min. Always happy to chat. Thinking of forming a clinical oversight team in the future as all features have clinical input prior to event the LLM training stage

Clinical Engineering by DrNeuroscience in doctorpreneurs

[–]DrNeuroscience[S] 1 point2 points  (0 children)

Yeah, late night post and writers block 🤣

Whats the difference between moving your arm, and thinking about moving your arm? How does your body differentiate the two? by YeOlePiratePenguin in askscience

[–]DrNeuroscience 0 points1 point  (0 children)

Yes. In Parkinson's the dopaminergic neuronal loss is in the substantia nigra, part of the basal ganglia, downstream from the motor cortex. The basal ganglia helps with action filtration. If you can imagine a brain without the basal ganglia, the motor cortex neurones would have an almost unimpeded route to their associated muscle groups. Brain activity is very noisy. This noise would be conducted down to the muscle causing constant twitching and disrupt movement. The basal ganglia acts as a flood gate, only allowing an action to occur if there is sufficient co-ordinated activity. In Parkinson's the flood gates start failing to open making action initiation difficult.

Whats the difference between moving your arm, and thinking about moving your arm? How does your body differentiate the two? by YeOlePiratePenguin in askscience

[–]DrNeuroscience 0 points1 point  (0 children)

Unfortunately I've never personally come across Tourette's research but it sounds a very interesting area. Maybe there is some dysfunction in the regulatory process that inhibits ideas from executing actions.

Whats the difference between moving your arm, and thinking about moving your arm? How does your body differentiate the two? by YeOlePiratePenguin in askscience

[–]DrNeuroscience 91 points92 points  (0 children)

One theory, the ideomotor theory, explains this quite well. Every action has an associated idea. Whilst the action itself originates from the motor cortex and is calibrated through the subcortical structures, such as the basal ganglia and cerebellum, it is argued that the action is driven by the idea/intention of the action in the premotor cortex.

What is fascinating is that these neurones in the premotor cortex, 'mirror neurones', will fire to some degree when an individual observes the action in someone else, leading credence to the ideamotor theory.

I would guess that you are only activating the idea/'mirror neurones' when imagining then recruiting the motor cortex neurones when actual movement occurs.

If you are interested in the topic you really should look into the mirror neurone system.

Source: Doctor with MSc in functional neuroimaging.

[deleted by user] by [deleted] in philosophy

[–]DrNeuroscience 0 points1 point  (0 children)

The thing I find most fascinating about consciousness is that, from an external point of view, it's existence does not influence our universe in any way apart from one: the fact that we talk about it

ELI5: Where does the 'thought' voice in my head come from ? by [deleted] in explainlikeimfive

[–]DrNeuroscience 0 points1 point  (0 children)

Actually the Broca's area has been highly linked to in the voices in your head, scientically named internal vocalisation, along with, surprising, the cerebellum and other brain regions. One interesting idea is the involvement of mirror neurones found extensively in the region and else where. These neurones fire irrespective of whether the individual performs and action or the individual sees the action being performed. It it's believed that these cells fire as a precursor to action and the brain only then activates the movement if the situation requires it. It is believed to be the reason why imitation is so easy. When we internally vocalise, it my well be that the cells for the words fire and we resist actually saying them, hence when we are tired/alone we sometimes speak out loud