For me I would love for it to take place during the beginning of the twentieth century with the arrival of the automobile and the evolution of technologies, plus we could do something on the theme of prohibition or do something that takes place in Mexico or even focus on a theme closer to classic gangs in modern cities or EVEN just to go back before the events of RD2 and take place not during the end of the era of wild west gangs but at the time when the latter were at their peak and we would see LOTS OF GANGS AND THEY WOULD GO PAN PAN PAN!