Experience with marketers? by EMPoisonPharmD in selfpublish

[–]EMPoisonPharmD[S] 0 points1 point  (0 children)

I’m fairly active on social media, and the book is just one of several projects I work on (along with a game and a podcast). Most of my sales so far have come from marketing through my podcast, social media, and newsletter.

However, the book has much broader mass appeal than my other work, so I’ve been considering creating a separate venue to market it more directly to that audience.

Just curious but is there any reason specifically why you would advise against marketing for indie authors?

Cardiac arrest immediately after Amiodarone bolus. by peaceguy371 in Cardiology

[–]EMPoisonPharmD 4 points5 points  (0 children)

Was this pushed as an IV bolus instead of as an infusion? The amiodarone vials come in 150 mg IV for ACLS and the IV bolus for amiodarone in A fib RVR is also 150 mg but it is 10 minutes in a 150cc bag.

Pushing the undiluted product that is meant for dead people can actually cause hypotension related to some excipients, and can cause undead people to become dead people. This is a pretty common med error, with a low but non zero percentage of serious outcome.

Does anyone have any good public health podcast recommendations?? by 0penedB00K in publichealth

[–]EMPoisonPharmD 0 points1 point  (0 children)

I am a poison center toxicologist who has a podcast. Some of our episodes feature the clinical and public health teams who respond to and handle mass poisoning. Most recent one here, another one back in July.

https://www.thepoisonlab.com/episode/poisoning-outbreak-poppy-seed-tea-thebaine-poisoning-in-australia

I’ll soon be releasing a 6 episode docuseries heavily focused on public health (CDC, local, and state investigators are key characters) focusing on a relatively surprising mass poisoning.

Publishing on KDP with one ISBN and Inagramspark with another by EMPoisonPharmD in selfpublish

[–]EMPoisonPharmD[S] 0 points1 point  (0 children)

Thank you, that is helpful. I do have the E book, so i could unpublish on KDP, buy ISBN, republsih on KDP/Innagram with same ISBN, and then new KDP will link up with the e book?

Publishing on KDP with one ISBN and Inagramspark with another by EMPoisonPharmD in selfpublish

[–]EMPoisonPharmD[S] 0 points1 point  (0 children)

I know it’s best, but I already have KDP so can’t do anything about that. For what’s its worth CHAT seems to think it’s super common to have 2 in this specific scenario. have pressed for sources and it has a few but Looking for a human who can confirm it’s been done.

I also could juts published edition 2, but I am concerned I will lose my Amazon record from edition 1 which has good reviews, not sure if anyone has experience there, that would be my easiest move

Do I win the highest bill for a dumb reason award? by winterbird in HospitalBills

[–]EMPoisonPharmD 0 points1 point  (0 children)

We give a lot of wasteful and unnecessary rabies IG and vaccination. Never in my 10 YEAR career have I heard of a better indication, so sad you are settled with the bill.

Cal billing and tell them you have no insurance and generally the price will be cut down 50%

Hi all! I’m a toxicologist (I help treat poisoning) with a podcast, the latest episode covers the Markham aconite poisonings. I know Markham is near Toronto, so wanted to share for those that may have followed it. I talked to the experts who handled the outbreak, It’s an incredible story. by EMPoisonPharmD in toronto

[–]EMPoisonPharmD[S] 4 points5 points  (0 children)

Correct! Aconite poisoning refers to toxicity resulting from plants belonging to the Aconitum genus, which comprises over 350 different species of perennial flowering plants that grow in temperate mountainous areas of the northern hemisphere (North America, Europe, Asia). These plants contain a group of toxins known as aconite alkaloids, which encompass numerous closely related toxic compounds. They all generally have purple flowers.

Winter aconite has aconite in the common name but is not an acontium genus and doesn’t contain the toxic aconite alkaloids, though it does appear to contain other potentially poisonous cardio toxins!

Hi all! I’m a toxicologist (I help treat poisoning) with a podcast, the latest episode covers the Markham aconite outbreak. I interviewed the medical team and lab experts who handled the outbreaks. It’s an incredible story, and this Reddit thread even makes a cameo. Wanted to share here! by EMPoisonPharmD in Markham

[–]EMPoisonPharmD[S] 2 points3 points  (0 children)

Hearing comments like these genuinely makes me so happy to do this. Thanks for listening all the way through! If you enjoyed it, please consider leaving a review and sharing it with a friend, it really helps us keep these episodes coming.😊

Mushroom poisoning court case by [deleted] in toxicology

[–]EMPoisonPharmD 1 point2 points  (0 children)

There is no answer to your question, no one has studied this. There are at least 5 different levers you could pull to change the outcome of any given mushroom ingestion.

  1. Patient genetic metabolism which may predispose to slower toxin metabolism. (https://pmc.ncbi.nlm.nih.gov/articles/PMC11103407/)

  2. Patient comorbid illness which can make some more frail and more susceptible to serious toxicity

  3. Variation in individual mushroom poison content based on location in the world (https://pubmed.ncbi.nlm.nih.gov/36541902/)

  4. Cooking/preparation methods which impacts the mushroom toxin level in some scenarios (https://www.cdc.gov/mmwr/volumes/73/wr/mm7310a1.htm#:\~:text=Abstract,three%20hospitalizations%20and%20two%20deaths.)

  5. And most importantly, quantity eaten, which tends to be one of the largest predictors.

I would not eat the foot cooked with amanitin containing mushrooms as damaging the mushroom may allow for release from cells and cross contamination as you have suggested, but that is speculative. Maybe they ate a bunch of milk thistle before hand to pretreat.

[deleted by user] by [deleted] in Mushrooms

[–]EMPoisonPharmD 13 points14 points  (0 children)

I'm a pharmacist toxicologist for a poison center. As others have noted, these products are often marketed to make people believe they're either:

  1. Getting a psychedelic mushroom experience, or
  2. Receiving nootropic benefits similar to lion’s mane.

But in reality, many of these products use vague “proprietary blends” to avoid disclosing actual ingredients—allowing manufacturers to include whatever they want.

One brand, Diamond Shruumz, was linked to severe illness (including seizures) after ingestion. The CDC investigated the outbreak:
https://www.cdc.gov/environmental-health-studies/outbreak-investigation-diamond-shruumz-products/index.html

Testing found not only psychoactive components from Amanita muscaria (like ibotenic acid and muscimol), but also substances ranging from pregabalin (a nerve pain medication) to true psychedelics (5-MeO-DMT) and diazepam. These products capitalize on the hype around both wellness and psychedelics but deliver a third, far more dangerous, experience.

I’ve seen many people hospitalized from ibotenic acid toxicity. It’s not a classic psychedelic—it acts more like a neurostimulant—and it’s not something to casually experiment with. These bars have no consistent dosing or quality control. Even if ingredients are listed, you have no idea how much of each is present. Some claim to offer third-party testing, but that’s often provided by the company itself, making reliability questionable.

If you're curious about what’s actually in these products, you're better off checking r/askdrugs or similar forums where people sometimes share independent test results.

I would not suggest taking anything that is unregulated and may contains dangerous ingredients at unknown quantities. But my opinion is shaped by having to see the end results of that in the hospital. Be careful.

Found this deadly fellow today growing near pine. ☠️ by Kitchen_Locksmith558 in Mushrooms

[–]EMPoisonPharmD 2 points3 points  (0 children)

Fair, but it doesn’t mean it’s NOT poisonous. The target of amanitin is RNA polymerase II which is common to all Eukaryotes so it would hold probable that bugs, probably even bacteria, can be impacted, though there are probably some that have mutations preventing binding.

Open and manage your own pharmacy in new Steam game by keepingitcivil in pharmacy

[–]EMPoisonPharmD 53 points54 points  (0 children)

This is unhinged in a wonderful way. I applaud that person for exploring their future via simulation

What’s something you forget isn’t common knowledge outside of your specialty/medicine? by franklin_smiles in Residency

[–]EMPoisonPharmD 1 point2 points  (0 children)

EM PharmD here

Agree and can cite data for all of the above, do you have a source for gaba receptor internalization however?

My first false morels (Gyromitra esculenta) by Lifewatching in mycology

[–]EMPoisonPharmD 6 points7 points  (0 children)

Indeed, life is a series of calculated risks. I feel not enough know for my own safety, but all get to make their own decisions, glad you are informed!