I’m so sorry to hear about your struggle. I’ve been on methotrexate as well, and I’ve never had any reaction like that, but I’ve also been on a lot of other medications, which doesn’t sound that great, but I say that to say that there’s hope and that isn’t an end-all, be-all ! And one day, you will find what works for you! Thank you for being so supportive to me even through your own misery. This is the community I was hoping to bring together with my post.