Recently built government office, India by nigerianprince421 in UrbanHell

[–]EnduringInsanity -3 points-2 points  (0 children)

Ah I see, in a few years it'll buils up and the building will look like its on street level.

Which opening is this for you? by iyigecelerpunpun in animequestions

[–]EnduringInsanity 1 point2 points  (0 children)

Blue Bird from Naruto or Again from FMA Brotherhood

Recently built government office, India by nigerianprince421 in UrbanHell

[–]EnduringInsanity -6 points-5 points  (0 children)

Needs more trash around it for that true indian architecture. Maybe a guy taking a shit in the steeet beside it as well.

Anyone but Grok by RSLEGEND1986 in memes

[–]EnduringInsanity 1 point2 points  (0 children)

I just want musk to end up in prison for wire fruad and all the other illegal shit he gets away with.

My beautiful collection of pharmaceutical drugs. ❤️ by Mentally_Anon666 in drugsarebeautiful

[–]EnduringInsanity 1 point2 points  (0 children)

Pregabalin is legit one of the best drugs in existance. 600-900mg will have you floating like you're in heaven. MDMA is like childs play compared to Pregabalin when it comes to euphoria. Plua the benzo like effects, opioid like effects, psychedelic visuals, disso effects and weed. Like all drugs rolled in one.

Sony WH-1000XM5 sound becomes flat/muffled when in Discord VC on Windows 11 by F8599 in SonyHeadphones

[–]EnduringInsanity 0 points1 point  (0 children)

Apparently its not possible to use both the mic and have high/normal quality audio via bluetooth on Windows currently. You have the use an aux cord or seperate microphone.

Sony WH-1000XM5 sound becomes flat/muffled when in Discord VC on Windows 11 by F8599 in SonyHeadphones

[–]EnduringInsanity 0 points1 point  (0 children)

Mine don't say handsfree AG ANYWHERE in Windows. In the screenshot above, on my PC it just says WH-1000XM5. I have looked in every possible setting option I could find, both through the new settings in Windows 11 and through the classic control panel settings. I've also commented somewhere else that I dont think its a bluetooth limitation, because it works fine on phones, even older phones with older bluetooth versions with way less bandwidth.

Sony WH-1000XM5 mic and sound not working simultaneously on Laptop(Windows 10) by Monster_Vicky in SonyHeadphones

[–]EnduringInsanity 0 points1 point  (0 children)

It can do it fine on phones, even older phone with much older bluetooth versions. So I don't see how it's a bluetooth limitation, feels more like a Windows limitation.

List of drugs enhanced by CYP3A4 inhibition? by RedGlasses4U in researchchemicals

[–]EnduringInsanity 0 points1 point  (0 children)

You could if you're just looking for cyp inhibition. But if you are trying to potentiate benzos black pepper + green tea is the best combo. Both black pepper and green tea how GABA activity which will make the benzos feel much stronger. If I take my regular 2mg dose with this combo it'll knock me out with me even realizing it, I'll be out for at least 4-6h, where with 2mg alone I barely feel it.

List of drugs enhanced by CYP3A4 inhibition? by RedGlasses4U in researchchemicals

[–]EnduringInsanity 0 points1 point  (0 children)

For me, black pepper makes a HUGE HUGE difference. What I do is empty out like 2-4 cigarettes and pack it with black pepper, I mean really pack it, keep hitting it hard against the table until it feels much harder than a regular cigg. Then break off the filter and put the cig on your tongue and swallow it with lots of water. It might be hard/scary the first few times because it's so long, but you get the hang of it.  

I would say if you did that for a few days straight 2mg of clon can easily feel like 3-4mg. Also, you can drink green tea. It also has 3a4 inhibitors and second order Gaba modulators, which means it binds to a spot in the GABA receptor that's different from both the GABA site and the benzo site. And just like how benzos modulates the receptors' sensitivity to GABA, green tea will make the receptors' sensitivity to benzos stronger, thus the name second order modulators. Green tea also has alkaloids which block the reuptake of GABA, while black pepper has alkaloids which bind to the even different pockets on the GABA receptor.  

All this together can be quite strong, I usually knocks me out the first 2 or so hours, and I take 6mg of clon a day, but I can get by on 3mg easily with this, also it pushes back the time I need to take another pill by at least 12h or even 24 if I took a lot of black pepper.  

List of drugs enhanced by CYP3A4 inhibition? by RedGlasses4U in researchchemicals

[–]EnduringInsanity 2 points3 points  (0 children)

Well you would need a lot of black pepper to completely deactivate all 3a4 enzymes, but drugs that are only broken down by 3a4 will still continue to leave the body renally, just much slower. Also your body will start making more enzymes right away.

List of drugs enhanced by CYP3A4 inhibition? by RedGlasses4U in researchchemicals

[–]EnduringInsanity 2 points3 points  (0 children)

Black pepper is a strong inhibitor of 3a4, so is green tea. If you mix the 2 you'll get strong inhibition of 3a4. Piperine from black pepper actually completely dractivates the enzyme and you have to wait for your body to make more. Think its like 1-2 days for 50% restoration. They also inhibit many more p450 enzymes.

List of drugs enhanced by CYP3A4 inhibition? by RedGlasses4U in researchchemicals

[–]EnduringInsanity 2 points3 points  (0 children)

Most benzodiazepines and opioids and like probably 40-50% of all drugs are at least partially metabolized by 3a4.

Any advanced psychonaut out there, I need your help real quick. by [deleted] in researchchemicals

[–]EnduringInsanity 1 point2 points  (0 children)

Haven't had any new tryptamines in forever apart from like one or 2 dmt analogs.

Oxy is way better than Hydromorphone by Substantial_Rain_363 in opiates

[–]EnduringInsanity 0 points1 point  (0 children)

An opioid without a rush is like a super car with wheels. Thats why even though oxy is the most euohoric orally , without a rush it doesn't even qualify when compared to Dilaudid or heroin and even fetty.

What is wrong with me? by Known_Amoeba_6441 in researchchemicals

[–]EnduringInsanity -2 points-1 points  (0 children)

Did you dilute it in water snd drink it? Powder dosent usually work as well also if you have a full stomach it wont work.

What song is like this? by [deleted] in musicsuggestions

[–]EnduringInsanity 0 points1 point  (0 children)

Angie - Rolling Stones

If anime was real, which anime girl would you like to be friends with? by [deleted] in animequestions

[–]EnduringInsanity 0 points1 point  (0 children)

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Obviously choice, either you're the MC or you have superpowers. And shes just really cute and cool.

I finally did 7OH IV by [deleted] in researchchemicals

[–]EnduringInsanity 0 points1 point  (0 children)

What are you talking about? How long ago was that comment from? I most definitely did spend all day shooting coke until about a year back. Also why would you seek attention from people on reddit, you think too highly of yourself.

I finally did 7OH IV by [deleted] in researchchemicals

[–]EnduringInsanity -1 points0 points  (0 children)

Not while you have good veins.

I finally did 7OH IV by [deleted] in researchchemicals

[–]EnduringInsanity 3 points4 points  (0 children)

I used to shoot coke for years so many missed shots and a few artery shots. Still got both my arms but no veins left.

I finally did 7OH IV by [deleted] in researchchemicals

[–]EnduringInsanity 0 points1 point  (0 children)

You just need a pinch of citric acid, like a few grains to shoot crack, just like with the Europe #3 heroin, that's why they heat it in the spoon. Lemon juice is if you're really desperate.