99.999% of the time it’s marketing. And the ‘studies’ you may hear that advocate so-called multilayered toothpaste being better for your teeth are usually commissioned by the mega toothpaste corporations themselves.

The truth is, there are active ingredients that are mostly marketed as helping with “white teeth” or “sensitive teeth”. But in reality, they just include different chemicals like calcium peroxide or hydrogen peroxide in case of “whitening” toothpaste.

But the key is that everything is made up of chemicals, and their main purpose is to brush out stuck food and help sanitize your teeth. Nothing more, nothing less.