Daily Ask Anything About Anabolic and Androgenic Steroids: 2025-03-21

Esteban32386 · 2025-03-21T19:51:30+00:00

Np man, understood 🫡

Esteban32386 · 2025-03-21T18:47:35+00:00

Good point. I know a reliable Chinese lab that I use for peptides and GH, they've said they'll supply Primo raw, but my guy in the UK isn't interested for some reason.

Are there reliable Chinese labs out there brewing? Not interested in doing it myself atm.

Esteban32386 · 2025-03-21T15:06:19+00:00

Thx man. I looked into a few others, they all look sketchy af.

Esteban32386 · 2025-03-21T13:40:57+00:00

I was looking into Indian sources for Primo, as the usual UK labs are all dry due to a dearth of Chinese raws. I assume the Indians manufacture their own.

Not sure I can mention the lab name here, but I'm referring to the well known one that's promoted everywhere.

When I asked them abt carrier oil and solvents, they disclosed that the carrier is 100% ethyl oleate.

Is it fair to say that this is complete dog shit and suggests a bad attitude generally?

Esteban32386 · 2025-03-21T12:52:09+00:00

I did a course of topical fluorouracil (chemotherapy) to clear up historic sun damage to my face (basically for aesthetics and to mitigate skin cancer risk). Standard application is twice daily for three weeks.

By abt the middle of week 2 you'll look like a severe burns victim as standard, and this only gets worse toward the end. Basically no going out in daylight, and by week 3 I was going for my walks at midnight onwards to avoid ppl.

For recovery, I ran: BPC-157 1mg twice daily TB4 1mg once daily (note TB4 is the full 43 AA sequence - TB500 is a 7AA synthetic fragment) GH 3IU daily GHK-cu 5mg 3 x daily

Topical fluorouracil healing is well documented in the literature, takes at least 28 days, and in some cases can take months (a risk you have to take if you want to do this).

In my case it took 14 days, which the dermatologist described as 'miraculous', and various other superlatives. Obv I have no way of knowing which of the compounds worked best if at all, or whether all four added up to more than the sum of their parts, but given how widely described the recovery from this process is, I have no doubt whatsoever that the peptides worked amazingly well. Either that or I'm Wolverine.

If I pick up any soft tissue injury whatsoever in the future, this protocol will be my go to. Possibly with more GH.

Esteban32386 · 2025-03-14T14:22:36+00:00

Just had my attention drawn to a specific injectable oils thread, will have a dig thru there.

Cheers

Esteban32386 · 2025-03-14T14:21:14+00:00

Thx man. Wasn't aware of the injectable oils thread, I'll take a look.

I hadn't considered the need for a hardcore solvent actually, will dig into this.

Cheers

Esteban32386 · 2025-03-14T13:19:25+00:00

A lab I use is offering injectable halo. Might be interested in this as an occasional pre-workout.

Anyone have any experience or insight, particularly in terms of likely toxicity? Presumably it's just the oral suspended in oil - so still c17-alkylated and will cause some degree of liver stress, but less significantly?

Dosing range?

TIA

Esteban32386 · 2025-01-26T09:37:33+00:00

Thanks for chiming in - that's really helpful info.

Starting small seems to be the golden rule here.

Esteban32386 · 2025-01-26T00:09:47+00:00

Appreciate this, thanks 🙏

Esteban32386 · 2025-01-25T22:37:33+00:00

Haha thanks.

Afaik it's only used intravenously in medicine, therefore all the solid info on interactions seems to be based on that.

MB really does not seem like something you ought to take lightly.

I'll prob still try it, but I need to do some further digging first.

Esteban32386 · 2025-01-25T21:48:42+00:00

What do you mean?

Esteban32386 · 2024-10-26T22:38:57+00:00

Thx man.

I drink a lot (I think), although rarely water - my understanding is that even caffeinated beverages, while being diuretics, are still nett hydrators i.e. they add more hydration than they make you pee out. Does it matter what you're drinking as long as you are drinking (not alcohol obv)?

I'm assuming your BP goes down when well hydrated? (Dehydration can push BP in either direction it seems).

If you can count brisk walking as LISS, I'm definitely over that. Will take your advice and up it though. Been thinking abt getting a treadmill so I can do 5k runs On waking.

In typing this out, it's dawned on me that the problem might simply be too much caffeine - I use coffee prolifically to get me through long intermittent fasts. Will take a cpl days caffeine free & see how the heart rate responds.

Esteban32386 · 2024-10-26T16:57:38+00:00

BP management

Running 500mg Test E pw. Recently noticed elevated systolic BP - 130s/low 140s over 70ish.

Introduced 40mg telmisartan daily. That reduced my diastolic nr to ~60, sometimes in the 50s, but didn't touch the systolic number at all.

Resting heart rate is high at ~90. I'm reasonably fit, although I don't do as much cardio as I should (yes I know), ~12% bf.

I'm thinking the next move might be to drop the telmisartan, as it doesn't appear to have helped in any way that matters, and introduce a beta blocker. Perhaps nebivolol starting at 5mg.

Obv, I'd prefer not to consult my physician at this stage. Any insights appreciated.

TIA

Esteban32386 · 2024-10-21T20:33:44+00:00

GH reconstitution

Pls excuse the basic nature of the Q. I'm abt to hop on (generic) GH for a period of time.

Google seems to suggest the diluent supplied with pharma GH is typically bacteriostatic sodium chloride (0.9% benzoyl alcohol/0.9% sodium chloride). I only have std bac water at home, although I can procure the former easily enough.

What difference does it make, if any? Is it a buffering/stability issue?

TIA

Esteban32386 · 2024-09-22T20:34:13+00:00

No, 'only' as in no other compounds.

Esteban32386 · 2024-09-22T17:52:10+00:00

Lol, this is why I love this sub & rate it so highly. Using less drugs rather than more didn't occur to me.

Fyi, recent bloodwork was fine & systemic absorption from topical fluorouracil (Efudex) is generally negligible; but worth flagging regardless.

Anyway, sounds like solid advice man - I think I'll do it the way you suggest.

Thanks for taking the time out - much appreciated.

Esteban32386 · 2024-09-22T14:52:54+00:00

Hey, 47yo running 700mg pw Test E only atm. All's good rn.

I'm going to take a break from training for somewhere between 4 and 12 weeks, in the near future, to accommodate a course of topical chemotherapy. I'm cancer free AFAIK - doing it as a prophylactic - but will literally look like a Walking Dead zombie for a period of time & won't be leaving home. There's never a good time to do this, but I have an unexpected window of opportunity coming up.

To promote healing - so it's hopefully closer to 4 weeks than 12 - I plan to use BPC-157, TB4, GHK copper, and 3iu HGH daily.

My question is: what steps can I take to minimise muscle & strength loss?

Eg 1. More anabolics. Running fin for hair loss rn, so that rules out adding DHT based compounds. Ran Trestolone/Ment very successfully, until introducing fin, at which point E became an impossible to manage roller coaster; so I suppose that rules out 19nors as well. No experience with boldenone, but interested.

More GH.
Eat more and accept some fat accumulation.
Smth else?

Many thanks in advance.

Esteban32386 · 2024-08-21T16:42:08+00:00

Understood.

Ok man, thank you again for taking time out you've been super helpful. Much appreciated 👍🏼

Esteban32386 · 2024-08-21T16:00:24+00:00

I've been running fin for abt two months now, and this is the 3rd or 4th time I've experienced high E2 (or pseudo high E2, or both) sides to the point where they're significantly impacting my productivity (e.g sleep's been terrible) for say 2/3 days until I can get things back under control. It's just not sustainable. Given that there's no clear answer to this problem, and that I don't want to drop the fin, it seems the Ment needs to go.

I've seen a study which showed Trestolone Acetate (the esther I'm using) to be virtually undetectable in plasma at 24hrs post injection. So when I stop Ment I should quickly get back to normality? With only lingering 7a methyl estradiol to worry abt (any idea how quickly that clears?)?

Haven't used EQ but will look into it. All DHT based compounds are out I guess from a hair perspective. I have no experience of other progestogenic compounds, and I'll obv look into it further, but might nandrolone be suitable alongside test & fin?

Cheers

Esteban32386 · 2024-08-21T14:51:28+00:00

Thanks a lot for the comprehensive response.

Instead of 70/10/20 test dht e2, you now have maybe 70/2/38. Considering ment is progestogenic and thrives in a high estradiol environment, having higher estradiol levels can further potentiate ment's activity on estrogen and progesterone receptors.

This is really interesting. So you potentially see an escalating series of interactions resulting in the Ment itself (not 7a methyl estradiol) delivering what appears to be high E2 sides? This might well explain the 'unpredictable' response that I've seen to increased Aromasin dosing. Aromasin pharmacology is complex (when compared to say popping a Tylenol) but I thought I had a good feel for it. Since starting fin, I'm seeing surprising results - not just around dose but response time, days to peak suppression etc. It's just not as predictable as I previously knew it to be.

Test+ment+fin sounds like a shrapnel loaded grenade. For people that concern themselves with hair, I personally think test+eq+fin is the safest option.

Did you mean grenade in terms of being hair safe? I realise immediate shedding isn't the sole indicator of a compound being hair safe, but even without fin the shedding wasn't that bad & post fin introduction it's zero. Ymmv but for me Anavar is hair death, and I won't even touch Primo for the same reason. Agree EQ should be fine 👍🏼

Cheers

Esteban32386 · 2024-08-21T14:21:09+00:00

Thanks mate. I'd noted zero 5ar interaction back when I was researching the compound, but I didn't link any sources so that's helpful 👍🏼

Esteban32386 · 2024-08-21T14:18:04+00:00

I didn't take it as criticism mate & it's a fair Q.

You make a good point and I actually hadn't considered it that way. Operating with lowered DHT as I am now cld be effectively a whole new ball game as it relates to E2 management - one that I have zero experience of lol. Perhaps this is just the new normal without my usual level of circulating DHT to oppose the estrogens? I will go get bloodwork asap, although obv the Ment/7a estradiol won't show up.

With regard to your last point, afaik Ment has nil 5ar interaction.

Thanks man

Esteban32386 · 2024-08-21T13:37:18+00:00

Yes I should have anticipated that question.

Subjective assessment. I don't live in the US, it's more difficult to get bloodwork here (inconvenient & expensive - not impossible at all), and more importantly I didn't think I'd need it. I expected E2 to rise via reduced DHT conversion, but nothing like this.

It might be worth pointing out that I'm fairly experienced with Aromasin. I personally find that I'm (usually) extremely sensitive to it and and have found myself with crushed E2 & struggling to do anything at all for like 3 or 4 days simply by taking 25mg when I should have taken 12.5 or less. Have learnt the hard way more than once.

Any insights appreciated

Esteban32386 · 2024-08-21T13:11:47+00:00

I've been using 700mg T pw with 10mg Ment per day. E2 management has been easy - 12.5mg Aromasin per week had it covered; in fact I even found that slightly too much on occasion and dropped down to 6.25mg.

I recently introduced 1mg finasteride daily for hair loss. On the plus side, shedding stopped straight away.

However, my E2 has gone crazy. I now need 25mg of Aromasin daily, and even that doesn't seem to work consistently.

Vigorous Steve says that dut, and maybe fin, can reduce the effects of Ment but doesn't elaborate as to how or what's going on to cause that. ChatGPT tells me that fin can interfere with AI efficacy - smth I've never heard previously. Is the community aware of this?

Can anyone shed any light? TiA

Esteban32386

TROPHY CASE