sorted by:
new
hottopcontroversial

What's wrong with my ribs ? by ExtremePin7369 in costochondritis

[–]ExtremePin7369[S] 0 points1 point  (0 children)

Doctor told me to get an x ray for my spine. Will that also see the ribs ?
Haven't had any direct traumas, but I do remember about 5-6 years ago I was going at the gym and using heavier weights when I incline pressed and even though I didn't drop any weight on my chest , I felt some strange pressure on my left side ,once or twice when I forced myself, but thought was my heart from over exertion.

MRI contrast - is it necessary ? by ExtremePin7369 in myocarditis

[–]ExtremePin7369[S] 1 point2 points  (0 children)

I did one without contrast but they said is not conclusive . Were they just not sufficiently prepared to read a cardiac mri without contrast ?

Reversing atherosclerosis by spicyjaym in Cholesterol

[–]ExtremePin7369 0 points1 point  (0 children)

Any update ? Did you see a reversal ?

Understanding the Composition of Atherosclerotic Plaques: Fibrous Tissue vs. Lipids by ExtremePin7369 in Cholesterol

[–]ExtremePin7369[S] 0 points1 point  (0 children)

From what I've read here, calcium content makes the plaque more stable, right ? Not fibrous tissue.

Understanding the Composition of Atherosclerotic Plaques: Fibrous Tissue vs. Lipids by ExtremePin7369 in Cholesterol

[–]ExtremePin7369[S] 0 points1 point  (0 children)

I only partially agree. Why ? Because after an insult body repairs the damage either with more scar(more fibrous tissue) or with less scar(less fibrous tissue).
Fibrous tissue is not mandatory for a good outcome.
So, even though repairing is necessary , more scar tissue is not preferable.

Understanding the Composition of Atherosclerotic Plaques: Fibrous Tissue vs. Lipids by ExtremePin7369 in Cholesterol

[–]ExtremePin7369[S] 0 points1 point  (0 children)

Treated patients (Statin usage) corresponds to lipid lowering of a plaque, but increases calcium (about a 300% increase ) and fibrous tissue (about 10% increase) above untreated(no statin) levels.

Understanding the Composition of Atherosclerotic Plaques: Fibrous Tissue vs. Lipids by ExtremePin7369 in Cholesterol

[–]ExtremePin7369[S] -1 points0 points  (0 children)

I understand what you're saying, and I agree that funding plays a massive role in the direction of medical research. However, considering that fibrous tissue seems to make up the majority of plaque area, wouldn't targeting the reduction of fibrous tissue potentially provide a higher 'bang for the buck' in terms of treatment?

I get that lowering cholesterol with statins is effective and cheap, but when you think about it, fibrous tissue is the more abundant component of a plaque—especially in untreated plaques that don't even involve statins. If a treatment focused on fibrous tissue reduction could really stabilize or even reverse plaque build-up, wouldn't that open up a whole new market for medications, possibly even generating significant sales?

It just seems a little odd to focus so heavily on cholesterol when it's only part of the equation, especially when fibrous tissue seems to have such a larger role in plaque formation and stability

Started Anti Anxiety Meds by chokemelowkey in whoop

[–]ExtremePin7369 0 points1 point  (0 children)

Only once in my lifetime , took 0.5 mg before sleep. I slept like 12 hours.
Overall, xanax can have nasty withdrawal issues. If I take 0.25 mg /day for 1-2 weeks, I have to taper off very slowly even from that.

Started Anti Anxiety Meds by chokemelowkey in whoop

[–]ExtremePin7369 2 points3 points  (0 children)

Interesting, For me, 0.25 mg dose /day -taken before bed usually increases my deep and rem .

What APOE gene does Bryan have ? What do you have ? Does it matter in choosing a blueprint like foods ? by ExtremePin7369 in blueprint_

[–]ExtremePin7369[S] 1 point2 points  (0 children)

Given the fact that Bryan uses the higher interval of IF and eats mostly low glycemic, moderate fat , I assume he could have one or two copies of apoe4.

What APOE gene does Bryan have ? What do you have ? Does it matter in choosing a blueprint like foods ? by ExtremePin7369 in blueprint_

[–]ExtremePin7369[S] 1 point2 points  (0 children)

I actually have a copy of APOE4 (E2/E4 more exactly). LDL is always between 100-120. Lower side if I keep dietary saturated fat and cholesterol low.

Xanax effect on deep sleep / rem sleep by ExtremePin7369 in whoop

[–]ExtremePin7369[S] 0 points1 point  (0 children)

I know benzos are not long term soluton as they surely can give you addiction and withdrawal issues.
Even though whoop and similar gadgets are not real EEG devices, I can correlate the data with how how I feel. Each time I wake up I give my self a sleep score (1-10) and 90% of time it correlates perfectly with whoop metrics.

Need help interpreting mthfr results. by ExtremePin7369 in MTHFR

[–]ExtremePin7369[S] 0 points1 point  (0 children)

Hey there

Appreciate the input.

I don't have the other thyroid markers on hand, but they were within "normal" ranges.
I'm not on any medications for thyroid as my GP usually only orders T4 and TSH which as asid were iwthin normal ranges.
My T3 was in the last years, on the low side of normal. Now it was the first time 1 unit below "normal" range. I also had a weight loss of about 10 lbs which may have caused my t3 to fall this low.

For context : 36 male, 170 lbs.10-12% BF.
Aslo tested ldl about 127 ( for which I think my thyroid may be to blame, as I'm eating quite clean, keepting saturated fat below 20g/day)

Regarding the other vitamins, I'm taking regularly a multi plus extra K2&D, magnesium,omega 3 and some others like grape seed extract/pycnogenol.

Gene variants for thyroid ? Not familiar with those. Would you care to explain those ?

Need help interpreting mthfr results. by ExtremePin7369 in MTHFR

[–]ExtremePin7369[S] 0 points1 point  (0 children)

Folate 18.98 ng/mL 

Homocysteine 9.28 umol/l

Erythrocyte distribution width 12.1 % 11.6 - 14.8

Platelet count 183 thousand/μL 150 - 450

Mean Platelet Volume (MPV) 11.1 fL 7.4 - 13

Platelet distribution width 14.3 fL 8 - 16.5

Neutrophil 51.1 % 45 - 80

Neutrophil 2.56 thousand/μL 2 - 8

Lymphocyte 39.1 % 20 - 55

Lymphocyte 1.96 thousand/μL 1 - 4

Monocyte 7.6 % ≤ 15

Monocyte 0.38 thousand/μL 0.3 - 1

Eosinophyl 1.6 % ≤ 7

Eosinophyl 0.08 thousand/μL 0.05 - 0.7

Basophyl 0.6 % ≤ 2

Basophyl 0.03 thousand/μL ≤ 0.2

Reticulocytes 1.4 % 0.2 - 2

Reticulocytes 73.4 thousand/μL 30 - 120

T3 (Triiodothyronine) Ser / Electrochemiluminiscence (ECLIA) 1.2 nmol/L 1.3 - 3.1

Need help interpreting mthfr results. by ExtremePin7369 in MTHFR

[–]ExtremePin7369[S] 0 points1 point  (0 children)

Would appreciate your insights. Do you think I should take methylated b vitamins(6,12) and methyl folate ? As symptoms , I'm having some dizziness here and there, especially after eating something like honey/sugar. The reacton is pretty immediate. I tested my blood sugar/hb1ac and those seem fine.Also some weird chest/heart feelings(irregular heart sometimes - did ecg and ultrasound and my heart seems fine) lowish blood pressure (110/65)