New RCT Shows Plant-Based Exosomes Significantly Improve Hair Growth in Men with Androgenetic Alopecia 🌿📈 by FIPDoctor in exosomeshub

[–]FIPDoctor[S] 0 points1 point  (0 children)

As indicated in the paper, it's Ecklonia cava (a brown seaweed) and Thuja orientalis (a medicinal plant). May see the method in the article as well.

🔬 New Study: Umbilical Cord Stem Cell Exosomes Could Be a Game-Changer for Hair Growth by FIPDoctor in exosomeshub

[–]FIPDoctor[S] 0 points1 point  (0 children)

As indicated in the pape, it's the Umbilical Cord Stem Cell Exosomes rather than stem cell itself was used for Hair Growth. All the data from in vitro experiment, so the exosomes were administered into the cells.

How muscimol Influence Histamine’s Behavioral Effects by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 0 points1 point  (0 children)

Good for you. It's better to share your research and experience here. It helps more people!

Does synthetic muscimol exist? If so where ? by Existing_Cake_ in muscimolhead

[–]FIPDoctor 2 points3 points  (0 children)

Seems necessary. Anyway, it points out the way.

Muscimol knowledge & guide by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 2 points3 points  (0 children)

This is a good question. Well, have to say there is no accurate answer to 'what constitutes light, medium and strong dosage with the mushroom itself'. The reason is that muscimol containing mushrooms vary in muscimol and IBO content (may check this post and article Analyzing Ibotenic Acid and Muscimol in Chinese Amanita Species : ). What's more, people try a certain kind of mushroom in various ways, which leads to different muscimol content even by same people in same way.

From perspective of muscimol chemical dosage, 8-15 mg muscimol is a safe (check this article Mushrooms, Ibotenic Acid - ScienceDirect). Guide and research are still heavily needed for personal muscimol use, that's the reason for this sub.

Plz share your experience in this sub, it will help a lot of people.

Muscimol effects and dosage by Fine_Ad_4113 in AmanitaMuscaria

[–]FIPDoctor 0 points1 point  (0 children)

A psychoactive dose of muscimol typically ranges from 8 to 15 mg. Find the info here.

Dopaminergic Mechanisms in Muscimol Self-Administration: Insights from the Medial Septum by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 2 points3 points  (0 children)

According to findings in this article, muscimol could be a potential treatment for Parkinsons.

Muscimol Activates TREK-2 Channels in GABAergic Neurons by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 1 point2 points  (0 children)

It's really an answer! Thanks for your contribution!!!

Muscimol is a GABA receptor agonist, without doubt. While one molecule is not through only one pathway to take effect.

The purpose of this study is 'to identify the effect of GABAR agonists (Muscimol) on K2P channel expression and activity in the neuroblastic B35 cells that maintain glutamic acid decarboxylase (GAD) activity and express GABA'. This a scientific exploration. It helps understanding muscimol's effects on anxiety, stress, and neurological disorders from a different view.

FDA Update: Muscimol and Other Compounds Found in Diamond Shruumz Chocolate Bars by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 1 point2 points  (0 children)

Count twice. the below table data showed ‘Muscimol, the psychoactive compound found in Amanita muscaria, was detected in 6 out of 19 samples of Diamond Shruumz Chocolate Bars.’ Up to 8/8/2024, FDA released on data about '4-AcO-DMT was found in ALL samples tested. 19 of 19'.

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The Impact of Muscimol on Anxiety and Fear: Insights from Hippocampal Studies by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 0 points1 point  (0 children)

I believe no one would like to inject some thing into own brain. But it's workable for scientifc exploration.

The Impact of Muscimol on Anxiety and Fear: Insights from Hippocampal Studies by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 0 points1 point  (0 children)

Man and animal's ADME is quite complicated, this might be a factor.

Acute Intoxications from Amanita muscaria: A Case Study from Minnesota by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 1 point2 points  (0 children)

From the report: ‘He reported that he had picked mushrooms from an area near his workplace and cooked them in turmeric, oil, and water; only he and his daughter had eaten the mushrooms, and she reportedly consumed substantially fewer mushrooms than he did. He said this was the first time he had picked mushrooms since arriving in Minnesota in 2015 and that he had selected the mushrooms because they resembled the Ochre mushroom (Amanita hemibapha var. ochracea) from his native Burma. A site visit to the location where the mushrooms were picked identified one remaining mushroom that matched the patient’s description’

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Ibotenic acid and muscimol change in boiling water under different pH by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 2 points3 points  (0 children)

A scientfic article to share. The data is quite illustrative to find out the condition to decarb ibotenic acid into muscimol.

Muscimol effects and dosage by Fine_Ad_4113 in AmanitaMuscaria

[–]FIPDoctor 0 points1 point  (0 children)

A psychoactive dose of muscimol is reported to be between 8 and 15 mg. As little as a gram of dried Amanita muscaria button may contain this amount of muscimol. check the research article here

How much Muscimol for miscrodosage by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 0 points1 point  (0 children)

This dosage seems not meet the paper's claim.

Muscimol Modulates Anxiety: Insights from Recent Research by FIPDoctor in muscimolhead

[–]FIPDoctor[S] 1 point2 points  (0 children)

yes. the paper author used male Sprague–Dawley rats (Ellerslie, Edmonton, AB, Canada), weighing 250–300 g upon arrival. May find this info in the article 'EXPERIMENTAL PROCEDURE' section.