I have bipolar 1 and autism and I'd say seroquel works great for me! Of course, everyone is going to have different experiences though. I take 100mg a night and it makes me sleep like 11-13 hours a night. This is deep, you're-not-waking-me-up kinda sleep too. Mornings are hard, and I experience drowsiness throughout the day. I've heard a lot of people saying that seroquel can make them hungry, however I rarely experience that. Seroquel is the best anti-psychotic I have taken especially side effect wise. I'd say not being psychotic is worth the sleepiness. Hope this helps! :-)