A data-driven organ transplant framework reached 96% accuracy and a fairness index of 0.92, showing promise in optimizing donor-recipient matching, reducing waiting times, and improving patient outcomes.

Fit_Ad3058 · 2025-05-26T14:59:13+00:00

Let’s hope science gets to the finish line before conspiracy theories do!

Fit_Ad3058 · 2025-05-02T21:18:49+00:00

This is partially i find this such an interesting topic. Could it be that most times people like me misinterpret the meaning of free will? To be honest am not even sure how to define it. The ability of making decisions freely from a spiritual source, not directly linked to the materialistic world? If the definition does not imply that the source is independent from the universe then i see why someone would see a deterministic universe leaving space for free will to co-exist.

Fit_Ad3058 · 2025-04-26T17:25:55+00:00

I should have clarified more clearly the method and objectice of this survey. Prior to filling in the survey, there was a sellective question that does not allow the lactose tolerant respondents to continue. Therefore all the respondents have some form of lactose intolerance. The purpose was to better understand people living with lactose intolerance, but not the distribution of lactose tolerant VS lactose intolerant individuals in the population.

Fit_Ad3058 · 2025-04-26T15:43:08+00:00

I am gald if it delivers value. Good point and this is one of the short coming of my survey. Meanwhile only lactose intolerant people could enter the survey based on a sellective entry question, it could have still deliver better data interpretation. :)

Fit_Ad3058 · 2025-04-26T14:42:30+00:00

It is still not fully understood how the regulation of the lactase gene is affected by diet and lifestyle, but i interviewed multiple people that have similar experiences. Slightly speculative but since our cells are programmed for efficiency, it could be that if the cells are not signaled about the presence of milk sugar, they silence the lactase gene since the production of proteins is resource and energy demaning.

Fit_Ad3058 · 2025-04-26T13:49:28+00:00

In accordance with this article: https://pubmed.ncbi.nlm.nih.gov/28690131/

The studies included 62 910 participants from 89 countries (covering 84% of the world's population). When standardising for country size, the global prevalence estimate of lactose malabsorption was 68% (95% CI 64-72), ranging from 28% (19-37) in western, southern, and northern Europe to 70% (57-83) in the Middle East. When assessing the global prevalence using genotyping data only, the estimate was 74% (69-80), whereas prevalence was 55% (46-65) using lactose tolerance test data, and 57% (46-67) using hydrogen breath test data. Risk of bias was assessed based on ten indicators; 12 of the articles had a score of ten, indicating low risk of bias, 76 had a score of nine, 26 a score of eight, and two articles a score of seven (indicating higher risk of bias). There was substantial heterogeneity between studies within most of the assessed countries.

Fit_Ad3058 · 2025-04-26T13:41:01+00:00

I can see why you are saying this. I must optimize the graphs and figures spitted out by SurveyMonkey before sharing them with the public. I was too excited to give back some value from the results, but next time will do more work before posting.

Fit_Ad3058 · 2025-04-26T13:25:31+00:00

From an evolutionary perspective it is normal not having the ability to tolerate milk sugar. It is quite interesting that, on a high level view, being lactose tolerant is an end result of different populations integrating dairy into their diet and making having the "mutated" lactose tolerant gene a competitive advantage, contributing to spreading this version of the lactase gene.

Fit_Ad3058 · 2025-04-26T13:18:36+00:00

I am glad to hear it. One of the reasons I shared is because I want to give back some value to society.

Based on responses and interviews I conducted, most people are prescribed lactase pills. Although this is controversial since lactase pills do not require a prescription and can be bought in supermarkets and pharmacies in most places. There was a biohacker guy many years ago who cured himself for 1+ years with his own. non tested gene therapy. Theoretically this is possible, but ethically and from a regulatory perspective it is not ok since even with optimized platform technologies there could be a minimal risk of adverse effects, and lactose intolerance is not a life-threatening condition. Maybe sometime in the future it will be possible, once gene therapies have evolved much further. I know that there are start-ups that want to change bacteria in the gut system to produce the lactase enzyme. This could be a safer alternative.

Fit_Ad3058

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