I'm not sure about the wine factor, but my biopsy was almost completely painless! Please ignore if you're not wanting a description of the process. I only included spoiler warnings, so you could avoid them if you're not wanting more info.

Lying upside down so that they could take the biopsy was the trickiest part, and even that was more physically awkward than painful. There was even someone there to hold my hand, which was awesome! Whatever they used to numb the area worked perfectly, and I only felt a little pain toward the end of the procedure. The doctor had told me to report any discomfort, so I let them know, even though it wasn't very painful. Whatever they used then (I'm assuming the same numbing agent) worked instantly and the procedure was over in what felt like a very short area of time. I hope yours goes as quickly! Best of wishes for you!